Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.32 |
| ▸ | CA4 | P22748 | 1/20 | 0.32 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9499497 | 0.76 | MAPK1 (0.35) | TSHRALDH1A1LMNAALOX12ACHE | |
| SCHEMBL1052821 | 0.72 | ALDH1A1 (0.41) | TSHRALDH1A1KIF11CES1PTPN1 | |
| SCHEMBL19235527 | 0.72 | MAPK1 (0.32) | ALDH1A1 | |
| SCHEMBL3202384 | 0.69 | — | — | |
| SCHEMBL10607277 | 0.68 | TSHR (0.38) | TSHRALDH1A1KIF11CA4CES1 | |
| SCHEMBL124751 | 0.67 | TSHR (0.39) | TSHRALDH1A1CA4LMNAALOX12 | |
| SCHEMBL55166 | 0.67 | — | — | |
| SCHEMBL1539360 | 0.67 | TSHR (0.39) | TSHRALDH1A1CA4LMNAALOX12 | |
| SCHEMBL7519286 | 0.67 | TSHR (0.32) | TSHRALDH1A1 | |
| SCHEMBL21120695 | 0.67 | RIPK1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6753401-B1 | DEHYDROGENATIVE POLYMERIZATION OF QUINONE AND/OR DIOL WITH TRIHYDROSILANE OR DIHYDROSILANE IN PRESENCE OF PALLADIUM-CONTAINING CATALYST; POLYSILANES | NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) | 2004-06-22 | — | — | US | disclosed |
| EP-1234829-A1 | SILICON-CONTAINING POLYMERS | National Institute of Advanced Industrial Science and Technology (JP) | 2002-08-28 | — | — | EP | disclosed |