Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3691011 | 0.71 | MAPK1 (0.36) | TSHRALDH1A1 | |
| SCHEMBL6835371 | 0.67 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL1052821 | 0.66 | ALDH1A1 (0.41) | TSHRALDH1A1 | |
| SCHEMBL6571982 | 0.64 | ALDH1A1 (0.52) | TSHRALDH1A1 | |
| SCHEMBL27959345 | 0.64 | MAPK1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL8374973 | 0.62 | ALDH1A1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL705029 | 0.62 | MAPK1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL10607277 | 0.62 | TSHR (0.38) | TSHRALDH1A1 | |
| SCHEMBL705415 | 0.62 | MAPK1 (0.33) | TSHRALDH1A1 | |
| SCHEMBL18398 | 0.61 | MAPK1 (0.36) | TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0900225-B1 | ALKYL-4-SILYL-PHENOLS AND ESTERS THEREOF AS ANTIATHEROSCLEROTIC AGENTS | AVENTIS PHARMA INC (US) | 2002-01-30 | — | — | EP | disclosed |
| US-5608095-A | Alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents | HOECHST MARION ROUSSEL, INC. (US) | 1997-03-04 | — | — | US | disclosed |