SCHEMBL68357

SCHEMBL68357

[CH2]CCCCCC1CCCO1

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 1/20 0.50
TP53 P04637 1/20 0.40
HPGD P15428 1/20 0.40
ALOX12 P18054 1/20 0.40
LMNA P02545 1/20 0.37
POLB P06746 1/20 0.37
USP2 O75604 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
ALDH1A1 P00352 4/20 0.34
TSHR P16473 2/20 0.33
KMT2A Q03164 3/20 0.32
MEN1 O00255 1/20 0.32
KDM4E B2RXH2 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6386082 0.98 EPHX1 (0.47) EPHX1TP53HPGDALOX12LMNA
SCHEMBL7290456 0.94 EPHX1 (0.48) EPHX1TP53HPGDALOX12LMNA
SCHEMBL9255771 0.92 EPHX1 (0.47) EPHX1TP53HPGDALOX12LMNA
SCHEMBL2047409 0.92 EPHX1 (0.45) EPHX1TP53HPGDALOX12LMNA
SCHEMBL1493226 0.91
SCHEMBL9264950 0.90 EPHX1 (0.44) EPHX1TP53HPGDALOX12LMNA
SCHEMBL29018576 0.89 EPHX1 (0.61) EPHX1ALDH1A1
SCHEMBL9256718 0.89 EPHX1 (0.61) EPHX1ALDH1A1
SCHEMBL3684347 0.89 EPHX1 (0.60) EPHX1TP53HPGDALOX12LMNA
SCHEMBL13294283 0.89 EPHX1 (0.60) EPHX1TP53HPGDALOX12LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 100 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2288340-B1 NANOPARTICLE FORMULATIONS AND USES THEREOF ABRAXIS BIOSCIENCE LLC (US) 2020-06-24 EP disclosed
EP-2416650-B1 NANOPARTICLE FORMULATIONS AND USES THEROF ABRAXIS BIOSCIENCE LLC (US) 2020-02-26 EP disclosed
US-10570431-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof NOVOZYMES, INC. (US) 2020-02-25 US disclosed
US-20180363018-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Heterocyclic Compound And Uses Thereof NOVOZYMES, INC. (US) 2018-12-20 US disclosed
US-20180289620-A1 NANOPARTICLE FORMULATIONS AND USES THEREOF ABRAXIS BIOSCIENCE, LLC 2018-10-11 US disclosed
US-10087478-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a nitrogen-containing compound and uses thereof NOVOZYMES, INC. (US) 2018-10-02 US disclosed
US-10041101-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof NOVOZYMES, INC. (US) 2018-08-07 US disclosed
EP-2603594-B1 COMPOSITIONS COMPRISING A POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A BICYCLIC COMPOUND AND USES THEREOF NOVOZYMES INC (US) 2018-04-25 EP disclosed
EP-2603598-B1 COMPOSITIONS COMPRISING A GH61 POLYPEPTIDE HAVING CELLULOLYTIC ENHANCING ACTIVITY AND A QUINONE COMPOUND AND USES THEREOF NOVOZYMES INC (US) 2018-04-18 EP disclosed
US-20180019412-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Quinone Compound And Uses Thereof NOVOZYMES, INC. (US) 2018-01-18 US disclosed
WO-1999024038-A1 METHODS FOR TREATMENT OF DISORDERS OF CARDIAC CONTRACTILITY JOHNS HOPKINS UNIVERSITY (US) 1999-05-20 WO disclosed
EP-0269859-B2 Pyrazolotriazine compounds OTSUKA PHARMA CO LTD (JP) 1995-10-18 EP disclosed
US-5455355-A Postemergence, preemergence herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-10-03 US disclosed
US-5358949-A Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1994-10-25 US disclosed
US-5298632-A Herbicidal pyrimidine compounds, compositions containing the same and method of use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-03-29 US disclosed
US-5232897-A Herbicidal pyrimidine compounds, compositions containing the same and method of use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-08-03 US disclosed
EP-0457505-A2 Pyrimidine derivatives and their use as herbicides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1991-11-21 EP disclosed
US-4824834-A TREATING GOUT OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) 1989-04-25 US disclosed
EP-0269859-A2 Pyrazolotriazine compounds OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1988-06-08 EP disclosed
EP-0236140-A2 Carbostyril derivatives and salts thereof and anti-arrhythmic agents containing the carbostyril derivatives OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1987-09-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180019412-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Quinone Compound And Uses Thereof PGLS, CEL, PNLIP EPHX1 1827/4885TP53 3378/4885HPGD 412/4885
US-20180289620-A1 NANOPARTICLE FORMULATIONS AND USES THEREOF ABCB1, SLC47A1, ABCC1 EPHX1 2975/4885TP53 21/4885HPGD 1328/4885
US-10570431-B2 Compositions comprising a polypeptide having cellulolytic enhancing activity and a heterocyclic compound and uses thereof CEL, VIP, CTRC EPHX1 1549/4885TP53 4220/4885HPGD 582/4885
US-20180363018-A1 Compositions Comprising A Polypeptide Having Cellulolytic Enhancing Activity And A Heterocyclic Compound And Uses Thereof CEL, VIP, CTRC EPHX1 1549/4885TP53 4220/4885HPGD 582/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.