Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | ALB | P02768 | 3/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.36 |
| ▸ | TRPM4 | Q8TD43 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833234 | 0.91 | KDM4C (0.43) | ROCK2SMN1; SMN2ALDH1A1USP2LMNA | |
| SCHEMBL6833880 | 0.88 | ALB (0.46) | ROCK2ALDH1A1USP2LMNANPSR1 | |
| SCHEMBL6818253 | 0.87 | ROCK2 (0.42) | ROCK2SMN1; SMN2LMNAALBGRM4 | |
| SCHEMBL6817988 | 0.87 | NAMPT (0.43) | ROCK2SMN1; SMN2PKMALDH1A1ALB | |
| SCHEMBL7128394 | 0.85 | SMN1; SMN2 (0.37) | ROCK2SMN1; SMN2HPGDPKMALDH1A1 | |
| SCHEMBL6814610 | 0.84 | ROCK2 (0.41) | ROCK2ALDH1A1LMNAALBGRM4 | |
| SCHEMBL6709950 | 0.82 | ROCK2 (0.39) | ROCK2SMN1; SMN2HPGDPKMALDH1A1 | |
| SCHEMBL6835744 | 0.81 | ALB (0.43) | ROCK2ALDH1A1ALBGRM4 | |
| SCHEMBL6708925 | 0.81 | ADORA2B (0.36) | ROCK2SMN1; SMN2HPGDLMNANPSR1 | |
| SCHEMBL6835702 | 0.80 | MAPT (0.47) | SMN1; SMN2HPGDALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ROCK2 4866/4885SMN1; SMN2 2022/4885HPGD 1657/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.