Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCL1 | Q07820 | 2/20 | 0.55 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.54 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.54 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.54 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.54 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | PHGDH | O43175 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833093 | 0.87 | MCL1 (0.56) | MCL1GRM4LMNAMAPTTP53 | |
| SCHEMBL6830542 | 0.86 | GRM4 (0.55) | MCL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6834152 | 0.85 | ALDH1A1 (0.49) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL6833315 | 0.85 | AKR1C2 (0.51) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL6834157 | 0.84 | POLB (0.53) | AKR1C4AKR1C3AKR1C2AKR1C1MEN1 | |
| SCHEMBL6830750 | 0.84 | HDAC3 (0.49) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT | |
| SCHEMBL6833056 | 0.83 | CNR2 (0.52) | AKR1C4AKR1C3AKR1C2AKR1C1MEN1 | |
| SCHEMBL418660 | 0.83 | MCL1 (0.57) | MCL1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6818878 | 0.83 | ALB (0.56) | MCL1GRM4LMNAMAPTTP53 | |
| SCHEMBL6830678 | 0.82 | AKR1C2 (0.48) | AKR1C4AKR1C3AKR1C2AKR1C1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | MCL1 2086/4885AKR1C4 2813/4885AKR1C3 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.