Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.49 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.49 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6834157 | 0.94 | POLB (0.53) | ALDH1A1TSHRHTTAKR1C2AKR1C1 | |
| SCHEMBL6833056 | 0.93 | CNR2 (0.52) | ALDH1A1TSHRHTTAKR1C2AKR1C1 | |
| SCHEMBL6830750 | 0.90 | HDAC3 (0.49) | ALDH1A1TSHRHTTAKR1C2AKR1C1 | |
| SCHEMBL6834054 | 0.87 | ALDH1A1 (0.49) | ALDH1A1TSHRHTTAKR1C2AKR1C1 | |
| SCHEMBL6834681 | 0.87 | CNR2 (0.48) | ALDH1A1TSHRHTTAKR1C2AKR1C1 | |
| SCHEMBL6830678 | 0.86 | AKR1C2 (0.48) | ALDH1A1TSHRHTTAKR1C2AKR1C1 | |
| SCHEMBL6835816 | 0.86 | CCR2 (0.58) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6835781 | 0.85 | MCL1 (0.55) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6834434 | 0.85 | CNR2 (0.50) | ALDH1A1TSHRHTTPOLBCNR2 | |
| SCHEMBL6834189 | 0.84 | AKR1C2 (0.48) | ALDH1A1TSHRHTTAKR1C2AKR1C1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | ALDH1A1 170/4885TSHR 3622/4885HTT 1599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.