SCHEMBL6835938

SCHEMBL6835938

Cc1cc(C)c2c(c1)CC(C)(c1cc(C)c(O)c(C)c1)C(C)(C)O2

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ACHE P22303 1/20 0.35
KDM4E B2RXH2 1/20 0.32
ALDH1A1 P00352 1/20 0.32
LMNA P02545 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13510784 0.71 DHFR (0.45) ALDH1A1LMNAMAPT
SCHEMBL17224775 0.65 ALOX5 (0.38) LMNA
SCHEMBL17224751 0.64 ALOX5 (0.35) LMNA
SCHEMBL27800318 0.63 ALDH1A1 (0.65) ACHEKDM4EALDH1A1LMNAGAA
SCHEMBL36529 0.63 ALDH1A1 (0.65) ACHEKDM4EALDH1A1LMNAGAA
SCHEMBL18528473 0.62 PPARA (0.36) KDM4EALDH1A1
SCHEMBL23667871 0.62 SELL (0.37) ACHEKDM4EALDH1A1LMNAGAA
SCHEMBL16316929 0.62 AKT1 (0.40) LMNA
SCHEMBL10400343 0.61 ALDH1A1 (0.62) ACHEKDM4EALDH1A1LMNAGAA
SCHEMBL14973508 0.61 ALDH1A1 (0.62) ACHEKDM4EALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756432-B2 POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-29 US disclosed
EP-0736574-B1 Thermoplastic resin composition comprising carbonate and acrylic resin GEN ELECTRIC (US) 2004-06-02 EP disclosed
US-20030153655-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 US disclosed
EP-0685526-B1 Fire-resistant polycarbonate resin composition GEN ELECTRIC (US) 2001-08-29 EP disclosed
US-6197917-B1 Method for manufacturing polycarbonate for optical use GENERAL ELECTRIC COMPANY 2001-03-06 US disclosed
CN-1062001-C A polycarbonate resin composition GEN ELECTRIC (US) 2001-02-14 CN disclosed
EP-1070743-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 2001-01-24 EP disclosed
US-6103827-A A TRANSPARENT THERMOPLASTIC RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2000-08-15 US disclosed
US-6043310-A FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. GENERAL ELECTRIC COMPANY (US) 2000-03-28 US disclosed
EP-0561630-B1 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LTD (JP) 1999-12-29 EP disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
US-5403878-A With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability CITIBANK, N.A., AS COLLATERAL AGENT 1995-04-04 US disclosed
US-5389713-A Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound GE PLASTICS JAPAN (JP) 1995-02-14 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed