Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 6/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.35 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | PPARA | Q07869 | 3/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.31 |
| ▸ | DHFR | P00374 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224775 | 0.87 | ALOX5 (0.38) | ALOX5NR1I2PPARGPPARAAKT1 | |
| SCHEMBL18528473 | 0.83 | PPARA (0.36) | ALOX5NR1I2PPARGPPARAAKT1 | |
| SCHEMBL13510784 | 0.72 | DHFR (0.45) | LMNADHFRTSHR | |
| SCHEMBL6835938 | 0.64 | ACHE (0.35) | LMNA | |
| SCHEMBL16316929 | 0.63 | AKT1 (0.40) | ALOX5NR1I2PPARGPPARAAKT1 | |
| SCHEMBL17224804 | 0.62 | USP2 (0.41) | LMNATSHR | |
| SCHEMBL8712759 | 0.62 | ALOX5 (0.33) | ALOX5NR1I2AKT1TSHR | |
| SCHEMBL8939958 | 0.62 | LMNA (0.39) | LMNA | |
| SCHEMBL12574869 | 0.62 | — | — | |
| SCHEMBL12035997 | 0.60 | ALDH1A1 (0.44) | LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3865480-B1 | HYDRAZINE DERIVATIVES | FMC CORP (US) | 2025-11-05 | — | — | EP | disclosed |
| CN-111018790-B | Pyridazinone herbicides | FMC公司 | 2023-09-19 | — | — | CN | disclosed |
| EP-3865480-A1 | HYDRAZINE DERIVATIVES | FMC Corporation (US) | 2021-08-18 | — | — | EP | disclosed |
| EP-3137456-B1 | PYRIDAZINONE HERBICIDES | FMC CORP (US) | 2021-06-02 | — | — | EP | disclosed |
| US-10597388-B2 | Pyridazinone herbicides | FMC CORPORATION (US) | 2020-03-24 | — | — | US | disclosed |
| US-20190016712-A1 | PYRIDAZINONE HERBICIDES | FMC CORPORATION | 2019-01-17 | — | — | US | disclosed |
| US-10118917-B2 | Pyridazinone herbicides | FMC CORPORATION | 2018-11-06 | — | — | US | disclosed |
| EP-3137456-A1 | PYRIDAZINONE HERBICIDES | E. I. du Pont de Nemours and Company (US) | 2017-03-08 | — | — | EP | disclosed |
| US-20170050953-A1 | PYRIDAZINONE HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 2017-02-23 | — | — | US | disclosed |
| WO-2015168010-A1 | PYRIDAZINONE HERBICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2015-11-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190016712-A1 | PYRIDAZINONE HERBICIDES | CBR3, NOX5, NR5A2 | ALOX5 673/4885NR1I2 83/4885PPARG 351/4885 |
| US-20170050953-A1 | PYRIDAZINONE HERBICIDES | CBR3, NOX5, NR5A2 | ALOX5 673/4885NR1I2 83/4885PPARG 351/4885 |
| US-10118917-B2 | Pyridazinone herbicides | CBR3, NOX5, NR5A2 | ALOX5 673/4885NR1I2 83/4885PPARG 351/4885 |
| US-10597388-B2 | Pyridazinone herbicides | CBR3, NOX5, NR5A2 | ALOX5 673/4885NR1I2 83/4885PPARG 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.