SCHEMBL6838424

SCHEMBL6838424

CCC(=O)Nc1ccc(C)cc1O

nearest known ligand 0.64

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
KMT2A Q03164 5/20 0.56
MEN1 O00255 3/20 0.56
CXCR2 P25025 1/20 0.55
GAA P10253 5/20 0.55
NPC1 O15118 4/20 0.55
RAB9A P51151 3/20 0.55
SMN1; SMN2 Q16637 2/20 0.52
ALDH1A1 P00352 1/20 0.51
HTT P42858 1/20 0.51
PKM P14618 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6836397 0.86 GAA (0.59) LMNAL3MBTL1KMT2AMEN1CXCR2
SCHEMBL6836552 0.86 KMT2A (0.61) LMNAKMT2AMEN1CXCR2GAA
SCHEMBL7764411 0.84 KMT2A (0.54) LMNAKMT2AMEN1CXCR2GAA
SCHEMBL6572962 0.84 ALDH1A1 (0.73) LMNAKMT2AMEN1CXCR2GAA
SCHEMBL2902945 0.84 KMT2A (0.79) LMNAL3MBTL1KMT2AMEN1GAA
SCHEMBL28515684 0.83 KMT2A (0.57) LMNAKMT2AMEN1CXCR2GAA
SCHEMBL15966067 0.82 L3MBTL1 (0.56) LMNAL3MBTL1KMT2AMEN1GAA
SCHEMBL6835468 0.81 GAA (0.61) LMNAL3MBTL1KMT2AMEN1CXCR2
SCHEMBL7763193 0.81 KMT2A (0.59) LMNAKMT2AMEN1CXCR2GAA
SCHEMBL27877164 0.81 CXCR2 (0.67) LMNAKMT2AMEN1CXCR2GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US claimed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US claimed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US disclosed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US disclosed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
US-5334225-A Imparts color tone of high chroma; excellent in coloring power and fastness KAO CORPORATION (JP) 1994-08-02 US disclosed
EP-0579204-A2 Dye composition for a keratinous fiber KAO CORPORATION (JP) 1994-01-19 EP disclosed