SCHEMBL6836397

SCHEMBL6836397

CCCC(=O)Nc1ccc(C)cc1O

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.59
NPC1 O15118 2/20 0.59
RAB9A P51151 2/20 0.59
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
ALDH1A1 P00352 1/20 0.54
LMNA P02545 2/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
PARP1 P09874 1/20 0.53
CXCR2 P25025 1/20 0.53
POLB P06746 1/20 0.53
HDAC3 O15379 1/20 0.51
HDAC4 P56524 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC7 Q8WUI4 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC10 Q969S8 1/20 0.51
HDAC11 Q96DB2 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
HDAC6 Q9UBN7 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21019394 0.87 GAA (0.72) GAANPC1RAB9AALDH1A1L3MBTL1
SCHEMBL6838424 0.86 LMNA (0.56) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6835468 0.85 GAA (0.61) GAANPC1RAB9AKMT2AMEN1
SCHEMBL25737020 0.85 MEN1 (0.74) GAAKMT2AMEN1ALDH1A1LMNA
SCHEMBL6836192 0.84 GAA (0.60) GAANPC1RAB9AKMT2AMEN1
Hydrochloric Acid SCHEMBL9313818 0.84 GAA (0.60) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6836552 0.83 KMT2A (0.61) GAANPC1RAB9AKMT2AMEN1
SCHEMBL7719074 0.83 GAA (0.76) GAANPC1RAB9AKMT2AMEN1
SCHEMBL6836390 0.83 NPC1 (0.62) GAANPC1RAB9AKMT2AMEN1
SCHEMBL11043074 0.82 L3MBTL1 (0.52) GAAKMT2AMEN1ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US claimed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US claimed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093792-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP claimed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP claimed
US-6752839-B1 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES L'OREAL (FR) 2004-06-22 US disclosed
US-6530960-B1 Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades L'OREAL S.A. (FR) 2003-03-11 US disclosed
EP-1093788-A1 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093789-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using the same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093793-A2 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093791-A1 Composition for oxidative dyeing of keratinous fibres and dyeing process using same L'OREAL (FR) 2001-04-25 EP disclosed
EP-1093790-A2 Oxydative dyeing composition for keratinic fibres and dyeing process using this composition L'OREAL (FR) 2001-04-25 EP disclosed
US-5334225-A Imparts color tone of high chroma; excellent in coloring power and fastness KAO CORPORATION (JP) 1994-08-02 US disclosed
EP-0579204-A2 Dye composition for a keratinous fiber KAO CORPORATION (JP) 1994-01-19 EP disclosed
US-4284704-A Photographic elements with incorporated hydrogen source photoreductant and tetrazolium salt EASTMAN KODAK COMPANY (US) 1981-08-18 US disclosed
US-RE30267-E SEMIPERMEABLE MEMBRANE, THIN FILM EASTMAN KODAK COMPANY (US) 1980-05-06 US disclosed
US-4066403-A DECOMPOSITION, PERMEABLE BARRIERS EASTMAN KODAK COMPANY (US) 1978-01-03 US disclosed