Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 6/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.50 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.50 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.50 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.50 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.50 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.50 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838424 | 0.86 | LMNA (0.56) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL13437936 | 0.85 | KMT2A (0.82) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7764411 | 0.84 | KMT2A (0.54) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6572962 | 0.84 | ALDH1A1 (0.73) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL28515684 | 0.83 | KMT2A (0.57) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6836397 | 0.83 | GAA (0.59) | KMT2AMEN1ALDH1A1HTTCXCR2 | |
| SCHEMBL6835468 | 0.81 | GAA (0.61) | KMT2AMEN1HTTCXCR2GAA | |
| SCHEMBL7763193 | 0.81 | KMT2A (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL27877164 | 0.81 | CXCR2 (0.67) | KMT2AMEN1SMN1; SMN2ALDH1A1CXCR2 | |
| SCHEMBL10176583 | 0.81 | MEN1 (0.59) | KMT2AMEN1SMN1; SMN2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6752839-B1 | 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES | L'OREAL (FR) | 2004-06-22 | — | — | US | claimed |
| US-6530960-B1 | Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades | L'OREAL S.A. (FR) | 2003-03-11 | — | — | US | claimed |
| EP-1093788-A1 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093790-A2 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093791-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093793-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093792-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| EP-1093789-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | claimed |
| US-6752839-B1 | 2-SUBSTITUTED 5-AMINOALKYLPHENOL DERIVATIVE COUPLER AND PYRAZOLES, CERTAIN PYRIMIDINES AND/OR PYRAZOLOPYRIMIDINES BASES; CHROMATIC, STRONG, AESTHETIC COLORATIONS IN VARIETY OF SHADES | L'OREAL (FR) | 2004-06-22 | — | — | US | disclosed |
| US-6530960-B1 | Oxidative base at least one 2-substituted 5-aminoalkylphenol coupler; chromatic, strong, aesthetic colorations in a variety of shades | L'OREAL S.A. (FR) | 2003-03-11 | — | — | US | disclosed |
| EP-1093788-A1 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093790-A2 | Oxydative dyeing composition for keratinic fibres and dyeing process using this composition | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093791-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093792-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093793-A2 | Composition for oxidative dyeing of keratinous fibres and dyeing process using same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| EP-1093789-A1 | Composition for oxidative dyeing of keratinous fibres and dyeing process using the same | L'OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| US-5334225-A | Imparts color tone of high chroma; excellent in coloring power and fastness | KAO CORPORATION (JP) | 1994-08-02 | — | — | US | disclosed |
| EP-0579204-A2 | Dye composition for a keratinous fiber | KAO CORPORATION (JP) | 1994-01-19 | — | — | EP | disclosed |