SCHEMBL6836847

SCHEMBL6836847

ClC1(Cl)c2ccccc2-c2ccccc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100A4 P26447 1/20 0.65
PDK2 Q15119 6/20 0.44
THRB P10828 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
KDM4E B2RXH2 2/20 0.41
LMNA P02545 2/20 0.41
MAPT P10636 2/20 0.41
KMT2A Q03164 2/20 0.41
MEN1 O00255 1/20 0.41
OPRK1 P41145 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
ITGA4 P13612 1/20 0.38
APEX1 P27695 1/20 0.37
ALDH1A1 P00352 2/20 0.36
CACNA1B Q00975 2/20 0.36
HSP90AA1 P07900 1/20 0.36
HSP90AB1 P08238 1/20 0.36
CACNB4 O00305 1/20 0.36
CACNA1A O00555 1/20 0.36
CACNA1G O43497 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29612259 1.00 S100A4 (0.65) S100A4PDK2THRBTDP1KDM4E
SCHEMBL27500046 0.97 S100A4 (0.62) S100A4PDK2THRBTDP1KDM4E
SCHEMBL28216738 0.97 S100A4 (0.62) S100A4PDK2THRBTDP1KDM4E
SCHEMBL9126309 0.84 S100A4 (0.61) S100A4THRBKDM4ELMNAMAPT
SCHEMBL8369793 0.83 S100A4 (0.46) S100A4PDK2THRBTDP1LMNA
SCHEMBL15745345 0.82 S100A4 (0.54) S100A4PDK2THRBTDP1KDM4E
SCHEMBL28469207 0.82 S100A4 (0.54) S100A4PDK2THRBTDP1KDM4E
SCHEMBL9270796 0.82 PDK2 (0.56) S100A4PDK2
Ammonia Solution, Strong SCHEMBL9520970 0.80 S100A4 (0.44) S100A4PDK2TDP1LMNAALDH1A1
SCHEMBL2599169 0.80 S100A4 (1.00) S100A4PDK2THRBTDP1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104280485-B A kind of simultaneous extraction, purify and detect the method for chloro polycyclic aromatic hydrocarbon in soil 南京大学 2016-11-30 CN claimed
CN-104280485-A Method for synchronously extracting and purifying various chlorinated polycyclic aromatic hydrocarbons in soil NANJING UNIVERSITY OF TECHNOLOGY 2015-01-14 CN claimed
CN-102875388-B Novel method for preparing 9,9-di(4-aminophenyl)fluorene JUNKAI TIANJIN CHEMICAL CO LTD 2014-09-03 CN claimed
CN-102875388-A Novel method for preparing 9,9-di(4-aminophenyl)fluorene JUNKAI TIANJIN CHEMICAL CO LTD 2013-01-16 CN claimed
CN-102391130-A Preparation method of 9, 9- diamino-(4-aminophenyl) fluorene SHANGHAI GUCHUANG CHEMICAL NEW MATERIALS CO LTD 2012-03-28 CN claimed
US-5387725-A Chlorinating compounds having acidic protons with a perchloro-alkane and aqueous base in the presence of a tetraalkyl-ammonium hydroxide phase transfer catalyst THE DOW CHEMICAL COMPANY (US) 1995-02-07 US claimed
EP-0611366-A1 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1994-08-24 EP claimed
US-5288915-A Process of making ketones THE DOW CHEMICAL COMPANY (US) 1994-02-22 US claimed
WO-1993009074-A2 CHLORINATION PROCESS, ALKYLATION OF PRODUCTS OF SAID PROCESS AND SOME PRODUCTS THEREOF THE DOW CHEMICAL COMPANY (US) 1993-05-13 WO claimed
EP-0308444-A1 PYRROL 1.2-b]AZINES MERCK PATENT GmbH (DE) 1989-03-29 EP claimed
WO-1988007702-A1 PYRROL [1.2-b]AZINES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-10-06 WO claimed
CN-115745761-B Preparation method of high-quality 9-fluorenone 中唯炼焦技术国家工程研究中心有限责任公司 2024-02-13 CN disclosed
US-20230240142-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240142-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
US-20230240142-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2023-07-27 US disclosed
WO-1988007702-A1 PYRROL [1.2-b]AZINES MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-10-06 WO disclosed
EP-0258504-A1 Fluorene polyarylate polymers and alloy compositions thereof CHEVRON RESEARCH AND TECHNOLOGY COMPANY (US) 1988-03-09 EP disclosed
US-4612350-A Bis(hydroxyphenyl)fluorene polyarylate polymers and alloys CHEVRON RESEARCH COMPANY (US) 1986-09-16 US disclosed
US-4510159-A (+)-Cyanidan-3-ol derivatives, pharmaceutical preparations that contain such compounds, and the use of the latter to treat liver or venous diseases ZYMA SA (CH) 1985-04-09 US disclosed
EP-0096008-A2 (+)-Cyanidan-3-ol derivatives, processes for their manufacture, pharmaceutical preparations that contain such compounds, and the use of the latter Zyma SA (CH) 1983-12-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230240142-A1 CONDENSED CYCLIC COMPOUND, LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE LIGHT-EMITTING DEVICE CRY1, CCNE2, NCAPH S100A4 3250/4885PDK2 766/4885THRB 4805/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.