Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3386796 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL9246457 | 0.77 | GPR3 (0.30) | — | |
| Hydrochloric Acid SCHEMBL2867400 | 0.76 | GPR3 (0.32) | — | |
| SCHEMBL10436063 | 0.65 | SLC6A2 (0.40) | — | |
| Hydrochloric Acid SCHEMBL2837147 | 0.64 | — | — | |
| Hydrochloric Acid SCHEMBL4499139 | 0.64 | GPR3 (0.32) | — | |
| Hydrochloric Acid SCHEMBL2480962 | 0.63 | — | — | |
| Hydrochloric Acid SCHEMBL7937640 | 0.63 | GPR3 (0.31) | — | |
| Hydrochloric Acid SCHEMBL6559595 | 0.63 | GPR3 (0.43) | — | |
| SCHEMBL6671925 | 0.62 | GPR3 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759499-B1 | POLYMER PRODUCTS HAVING NARROW COMPOSITION DISTRIBUTIONS, LOW MELT INDEX RATIOS, AND, OPTIONALLY, HIGH MELT STRENGTH | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-07-06 | — | — | US | disclosed |