Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6836906 | 0.80 | — | — | |
| Hydrochloric Acid SCHEMBL7106055 | 0.72 | BCHE (0.36) | — | |
| Hydrochloric Acid SCHEMBL9246457 | 0.72 | GPR3 (0.30) | — | |
| SCHEMBL27900768 | 0.67 | BCHE (0.33) | — | |
| Hydrochloric Acid SCHEMBL15948186 | 0.67 | — | — | |
| Hydrochloric Acid SCHEMBL3394335 | 0.65 | — | — | |
| Hydrochloric Acid SCHEMBL1141299 | 0.63 | — | — | |
| SCHEMBL4034020 | 0.61 | ACHE (0.47) | — | |
| SCHEMBL8086443 | 0.61 | GPR3 (0.41) | — | |
| SCHEMBL27546444 | 0.60 | BCHE (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7829495-B2 | Olefin polymerization process with alkyl-substituted metallocenes | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2010-11-09 | — | — | US | disclosed |
| US-6759499-B1 | POLYMER PRODUCTS HAVING NARROW COMPOSITION DISTRIBUTIONS, LOW MELT INDEX RATIOS, AND, OPTIONALLY, HIGH MELT STRENGTH | EXXONMOBIL CHEMICAL PATENTS INC. | 2004-07-06 | — | — | US | disclosed |
| US-6489413-B1 | AN OLEFIN POLYMERIZATION PROCESS COMPRISING CONTACTING ETHYLENE, ALONE OR WITH ONE OR MORE OLEFINICALLY UNSATURATED COMONOMERS, UNDER SUITABLE POLYMERIZATION CONDITIONS WITH A GROUP 3-6 METALLOCENE CATALYST COMPOUND CONTAINING TWO | EXXONMOBIL CHEMICAL PATENTS INC. | 2002-12-03 | — | — | US | disclosed |