SCHEMBL6836965

SCHEMBL6836965

CCc1ccc2c(c1)C(C)(C)CC(C)(c1cc(CC)c(O)c(CC)c1)O2

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.38
PARP1 P09874 1/20 0.34
SSTR5 P35346 1/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
TRPA1 O75762 1/20 0.31
PDK2 Q15119 1/20 0.31
EDNRA P25101 1/20 0.30
HCAR3 P49019 1/20 0.30
HCAR2 Q8TDS4 1/20 0.30
MAPT P10636 1/20 0.30
RAB9A P51151 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7780203 0.88 FTO (0.38) FTOPARP1SSTR5MEN1KMT2A
SCHEMBL6910911 0.80 AKR1B1 (0.37) PARP1SSTR5MEN1KMT2ACNR1
SCHEMBL6911113 0.78 FTO (0.39) FTOPARP1CNR1CNR2TRPA1
SCHEMBL27350972 0.74 MEN1 (0.32) PARP1MEN1KMT2AEDNRAMAPT
SCHEMBL27458584 0.74 MEN1 (0.32) PARP1MEN1KMT2AEDNRAMAPT
SCHEMBL27447416 0.74 MEN1 (0.32) PARP1MEN1KMT2AEDNRAMAPT
SCHEMBL27457712 0.74 MEN1 (0.32) PARP1MEN1KMT2AEDNRAMAPT
SCHEMBL6838753 0.71 FTO (0.41) FTOMEN1KMT2ACNR2MAPT
SCHEMBL6664115 0.71 FTO (0.50) FTOPARP1CNR1CNR2TRPA1
SCHEMBL31545161 0.71 FTO (0.50) FTOPARP1CNR1CNR2TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756432-B2 POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-29 US disclosed
EP-0736574-B1 Thermoplastic resin composition comprising carbonate and acrylic resin GEN ELECTRIC (US) 2004-06-02 EP disclosed
US-20030153655-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 US disclosed
US-6197917-B1 Method for manufacturing polycarbonate for optical use GENERAL ELECTRIC COMPANY 2001-03-06 US disclosed
EP-1070743-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 2001-01-24 EP disclosed
US-6103827-A A TRANSPARENT THERMOPLASTIC RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2000-08-15 US disclosed
EP-0561630-B1 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LTD (JP) 1999-12-29 EP disclosed
US-5883194-A RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS GENERAL ELECTRIC COMPANY (US) 1999-03-16 US disclosed
EP-0736574-A2 Thermoplastic resin composition comprising carbonate and acrylic resin GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0736558-A2 A polyester polycarbonate composition which is transparent and has outstanding thermal stability GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
US-5403878-A With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability CITIBANK, N.A., AS COLLATERAL AGENT 1995-04-04 US disclosed
US-5389713-A Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound GE PLASTICS JAPAN (JP) 1995-02-14 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed