SCHEMBL7780203

SCHEMBL7780203

CCc1ccc2c(c1)C(C)(C)CC(C)(c1cc(C)c(O)c(C)c1)O2

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.38
PTGS1 P23219 2/20 0.37
PTGS2 P35354 2/20 0.37
ALOX5 P09917 1/20 0.37
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
PARP1 P09874 1/20 0.32
ACHE P22303 1/20 0.31
TRPA1 O75762 1/20 0.31
SSTR5 P35346 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
TP53 P04637 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
RAB9A P51151 1/20 0.31
KMT2A Q03164 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6836965 0.88 FTO (0.38) FTOCNR1CNR2PARP1TRPA1
SCHEMBL6911113 0.85 FTO (0.39) FTOPTGS1PTGS2ALOX5CNR1
SCHEMBL6838753 0.84 FTO (0.41) FTOPTGS1PTGS2ALOX5CNR2
SCHEMBL7738835 0.80 FTO (0.39) FTOPTGS1PTGS2ALOX5ACHE
SCHEMBL6664115 0.71 FTO (0.50) FTOCNR1CNR2PARP1TRPA1
SCHEMBL31545161 0.71 FTO (0.50) FTOCNR1CNR2PARP1TRPA1
SCHEMBL4631373 0.71 FTO (0.44) FTOCNR1CNR2TRPA1ALDH1A1
SCHEMBL6911177 0.70 AKR1C1 (0.41) FTOTSHRTDP1
SCHEMBL7738828 0.68 LMNA (0.51) FTOACHEMEN1ALDH1A1TP53
SCHEMBL6910911 0.68 AKR1B1 (0.37) CNR1CNR2PARP1TRPA1SSTR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685526-B1 Fire-resistant polycarbonate resin composition GEN ELECTRIC (US) 2001-08-29 EP disclosed
US-6043310-A FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. GENERAL ELECTRIC COMPANY (US) 2000-03-28 US disclosed
EP-0685526-A2 Fire-resistant polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1995-12-06 EP disclosed