SCHEMBL6911113

SCHEMBL6911113

CCc1ccc2c(c1)C(C)(C)CC(C)(c1cc(C)cc(C)c1O)O2

nearest known ligand 0.39

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.39
ALDH1A1 P00352 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
ALOX5 P09917 1/20 0.33
PTGS1 P23219 1/20 0.33
PTGS2 P35354 1/20 0.33
CNR1 P21554 3/20 0.32
CNR2 P34972 3/20 0.32
TRPA1 O75762 1/20 0.31
TRPV1 Q8NER1 1/20 0.31
TRPV3 Q8NET8 1/20 0.31
TRPV4 Q9HBA0 1/20 0.31
TRPV2 Q9Y5S1 1/20 0.31
PARP1 P09874 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631373 0.87 FTO (0.44) FTOALDH1A1L3MBTL1CNR1CNR2
SCHEMBL7780203 0.85 FTO (0.38) FTOALDH1A1ALOX5PTGS1PTGS2
SCHEMBL6836965 0.78 FTO (0.38) FTOCNR1CNR2TRPA1PARP1
SCHEMBL9418454 0.77 ALDH1A1 (0.32) ALDH1A1L3MBTL1ALOX5PTGS1PTGS2
SCHEMBL27551135 0.75 ALDH1A1 (0.30) ALDH1A1L3MBTL1ALOX5PTGS1PTGS2
SCHEMBL27360492 0.75 ALDH1A1 (0.30) ALDH1A1L3MBTL1ALOX5PTGS1PTGS2
SCHEMBL6838753 0.75 FTO (0.41) FTOALDH1A1L3MBTL1ALOX5PTGS1
SCHEMBL7525551 0.72 FTO (0.54) FTOALDH1A1L3MBTL1CNR1CNR2
SCHEMBL31545161 0.72 FTO (0.50) FTOCNR1CNR2TRPA1TRPV1
SCHEMBL6664115 0.72 FTO (0.50) FTOCNR1CNR2TRPA1TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0736574-B1 Thermoplastic resin composition comprising carbonate and acrylic resin GEN ELECTRIC (US) 2004-06-02 EP disclosed
EP-0685526-B1 Fire-resistant polycarbonate resin composition GEN ELECTRIC (US) 2001-08-29 EP disclosed
US-6197917-B1 Method for manufacturing polycarbonate for optical use GENERAL ELECTRIC COMPANY 2001-03-06 US disclosed
EP-1070743-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 2001-01-24 EP disclosed
US-6103827-A A TRANSPARENT THERMOPLASTIC RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2000-08-15 US disclosed
EP-0561630-B1 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LTD (JP) 1999-12-29 EP disclosed
US-5883194-A RADIATION TRANSPARENT THERMOPLASTIC RESINS OF CARBONATE AND ESTER BLENDS WITH ACRYLATE RESINS AND CATALYSTS GENERAL ELECTRIC COMPANY (US) 1999-03-16 US disclosed
EP-0736574-A2 Thermoplastic resin composition comprising carbonate and acrylic resin GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0736558-A2 A polyester polycarbonate composition which is transparent and has outstanding thermal stability GENERAL ELECTRIC COMPANY (US) 1996-10-09 EP disclosed
EP-0694581-A2 A polycarbonate resin composition GENERAL ELECTRIC COMPANY (US) 1996-01-31 EP disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
US-5403878-A With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability CITIBANK, N.A., AS COLLATERAL AGENT 1995-04-04 US disclosed
US-5389713-A Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound GE PLASTICS JAPAN (JP) 1995-02-14 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed