SCHEMBL6838753

SCHEMBL6838753

Cc1ccc2c(c1)C(C)(C)CC(C)(c1cc(C)c(O)c(C)c1)O2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FTO Q9C0B1 2/20 0.41
ACHE P22303 1/20 0.34
L3MBTL1 Q9Y468 3/20 0.32
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
MAPT P10636 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
CNR2 P34972 1/20 0.32
CA1 P00915 1/20 0.32
CA2 P00918 1/20 0.32
ALDH1A1 P00352 1/20 0.31
ALOX5 P09917 2/20 0.31
PTGS1 P23219 2/20 0.31
PTGS2 P35354 2/20 0.31
GAA P10253 1/20 0.31
G6PD P11413 1/20 0.31
CYP26A1 O43174 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4631373 0.86 FTO (0.44) FTOL3MBTL1LMNAMAPTTDP1
SCHEMBL7738835 0.84 FTO (0.39) FTOACHEL3MBTL1MEN1KMT2A
SCHEMBL7780203 0.84 FTO (0.38) FTOACHEMEN1KMT2AMAPT
SCHEMBL7525551 0.81 FTO (0.54) FTOL3MBTL1MEN1KMT2ALMNA
SCHEMBL7520930 0.80 FTO (0.52) FTOLMNATDP1CNR2
SCHEMBL4631356 0.78 AKR1B1 (0.34) ACHEL3MBTL1MEN1KMT2AMAPT
SCHEMBL6911113 0.75 FTO (0.39) FTOL3MBTL1CNR2ALDH1A1ALOX5
SCHEMBL6911177 0.74 AKR1C1 (0.41) FTOTDP1
SCHEMBL7522360 0.74 KDM4E (0.34) FTOMEN1KMT2ALMNAMAPT
SCHEMBL9008421 0.71 FTO (0.52) FTOL3MBTL1MEN1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6756432-B2 POLYBUTADIENE TYPE POLYMER WITH A 1-BENZOPYRAN, A 1-BENZO PYRAN-2-ONE OR A BENZOIN DERIVATIVE; MOLDS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2004-06-29 US disclosed
EP-0736574-B1 Thermoplastic resin composition comprising carbonate and acrylic resin GEN ELECTRIC (US) 2004-06-02 EP disclosed
US-20030153655-A1 Polybutadiene composition SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-08-14 US disclosed
EP-0685526-B1 Fire-resistant polycarbonate resin composition GEN ELECTRIC (US) 2001-08-29 EP disclosed
US-6197917-B1 Method for manufacturing polycarbonate for optical use GENERAL ELECTRIC COMPANY 2001-03-06 US disclosed
CN-1062001-C A polycarbonate resin composition GEN ELECTRIC (US) 2001-02-14 CN disclosed
EP-1070743-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 2001-01-24 EP disclosed
US-6103827-A A TRANSPARENT THERMOPLASTIC RESIN BLENDS GENERAL ELECTRIC COMPANY (US) 2000-08-15 US disclosed
US-6043310-A FIRE-RESISTANT POLYCARBONATE RESIN COMPOSITION CONTAINING LIQUID CRYSTAL POLYMER, FLAME RETARDANT, POLYTETRAFLUOROETHYLENE. GENERAL ELECTRIC COMPANY (US) 2000-03-28 US disclosed
EP-0561630-B1 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LTD (JP) 1999-12-29 EP disclosed
US-5418269-A Made by ester interchange, mold release, thermal stability, little discoloration on molding, disks GE PLASTICS JAPAN (JP) 1995-05-23 US disclosed
US-5403878-A With alpha olefin oligomer and acidic sulfur compound; mold releasing, thermostability CITIBANK, N.A., AS COLLATERAL AGENT 1995-04-04 US disclosed
US-5389713-A Polycarbonate formed by melt polymerization of aromatic dihydroxy compound and carbonate diester, alpha-olefin oligomer, acidic sulfur-containing compound GE PLASTICS JAPAN (JP) 1995-02-14 US disclosed
EP-0605157-A2 Resin compositions GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
EP-0605194-A2 Transparent polycarbonate-polyester-blends GE PLASTICS JAPAN LIMITED (JP) 1994-07-06 EP disclosed
US-5276109-A Molding materials with transparency GENERAL ELECTRIC COMPANY (US) 1994-01-04 US disclosed
EP-0561638-A1 Optical-grade polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561629-A2 Polycarbonate resin compositions GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0561630-A2 Polycarbonate resin compositions for optical use GE PLASTICS JAPAN LIMITED (JP) 1993-09-22 EP disclosed
EP-0520806-A2 Optical polycarbonate compositions GE PLASTICS JAPAN LIMITED (JP) 1992-12-30 EP disclosed