SCHEMBL6837520

SCHEMBL6837520

CN(C)c1cccc2c1Cc1c-2cccc1N(C)C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.44
GAA P10253 4/20 0.44
KDM4E B2RXH2 3/20 0.44
ALDH1A1 P00352 4/20 0.44
L3MBTL1 Q9Y468 2/20 0.44
NSD2 O96028 1/20 0.44
EGFR P00533 1/20 0.44
LMNA P02545 1/20 0.44
MAPK1 P28482 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
TYR P14679 1/20 0.43
PDK2 Q15119 1/20 0.36
TSHR P16473 2/20 0.35
TP53 P04637 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HTR6 P50406 2/20 0.35
CHEK1 O14757 1/20 0.34
NEK2 P51955 1/20 0.34
LIMK1 P53667 1/20 0.34
DYRK1A Q13627 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30341585 0.86 PNMT (0.49) MAPTGAAKDM4EALDH1A1L3MBTL1
SCHEMBL1509311 0.86 PNMT (0.49) MAPTGAAKDM4EALDH1A1L3MBTL1
Hydrochloric Acid SCHEMBL2870709 0.84 PNMT (0.47) MAPTGAAKDM4EALDH1A1L3MBTL1
SCHEMBL20887133 0.76 CES1 (0.41) MAPTGAAKDM4EALDH1A1L3MBTL1
Ammonia Solution, Strong SCHEMBL28512747 0.74 MAPT (0.43) MAPTGAAKDM4EALDH1A1L3MBTL1
SCHEMBL8638275 0.74 TDP1 (0.40) MAPTGAAKDM4EALDH1A1L3MBTL1
SCHEMBL4812007 0.73 ALDH1A1 (0.46) MAPTGAAKDM4EALDH1A1L3MBTL1
SCHEMBL30524295 0.71 GFER (0.50) MAPTGAAKDM4EALDH1A1L3MBTL1
SCHEMBL2919461 0.71 MAPT (0.52) MAPTGAAKDM4EALDH1A1L3MBTL1
SCHEMBL26185701 0.70 MAPT (0.48) MAPTGAAKDM4EALDH1A1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6753128-B2 BLOCKING ACID GENERATION DURING PHOTOLITHOGRAPHY HYNIX SEMICONDUCTOR INC. (KR) 2004-06-22 US claimed
US-20030082481-A1 Photoresist additive for preventing acid migration and photoresist composition comprising the same HYNIX SEMICONDUCTOR INC. (KR) 2003-05-01 US claimed
US-6753128-B2 BLOCKING ACID GENERATION DURING PHOTOLITHOGRAPHY HYNIX SEMICONDUCTOR INC. (KR) 2004-06-22 US disclosed
US-20030082481-A1 Photoresist additive for preventing acid migration and photoresist composition comprising the same HYNIX SEMICONDUCTOR INC. (KR) 2003-05-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030082481-A1 Photoresist additive for preventing acid migration and photoresist composition comprising the same RARG, ELMO1, COL2A1 MAPT 1457/4885GAA 355/4885KDM4E 4226/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.