Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 2/20 | 0.34 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.33 |
| ▸ | ARF6 | P62330 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
| ▸ | NOS2 | P35228 | 2/20 | 0.32 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | ACP1 | P24666 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6838584 | 0.99 | ADORA3 (0.39) | ADORA3NPY1RPIM1SOS1ARF6 | |
| SCHEMBL6833984 | 0.90 | ADORA3 (0.37) | ADORA3NPY1RSOS1SLC6A4NOS1 | |
| SCHEMBL6833816 | 0.89 | ADORA3 (0.37) | ADORA3SOS1ARF6NPC1RAB9A | |
| SCHEMBL6838083 | 0.89 | ADORA3 (0.36) | ADORA3NPY1RSOS1CYP2D6SLC6A4 | |
| SCHEMBL6837640 | 0.89 | ADORA3 (0.38) | ADORA3SOS1ARF6CYP1A2CYP2D6 | |
| SCHEMBL6840005 | 0.88 | ADORA3 (0.35) | ADORA3NPY1RSOS1ARF6NOS1 | |
| SCHEMBL6838003 | 0.88 | ADORA3 (0.37) | ADORA3SOS1ARF6CYP1A2CYP2D6 | |
| SCHEMBL6833712 | 0.87 | ADORA3 (0.46) | ADORA3NPY1RTP53MAPT | |
| SCHEMBL6837810 | 0.87 | ADORA3 (0.37) | ADORA3SOS1ARF6SLC6A4ACP1 | |
| SCHEMBL6838758 | 0.86 | ADORA3 (0.45) | ADORA3NPY1RACP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | IL2, IL1A, IL4 | ADORA3 3201/4885NPY1R 1070/4885PIM1 261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.