Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | ARF6 | P62330 | 1/20 | 0.33 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.33 |
| ▸ | KHK | P50053 | 2/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | AXL | P30530 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.32 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6840005 | 0.99 | ADORA3 (0.35) | ADORA3ARF6TRIM58ALOX5APTLR7 | |
| SCHEMBL6833984 | 0.90 | ADORA3 (0.37) | ADORA3TRIM58TLR7HTR2CHRH1 | |
| SCHEMBL6837685 | 0.89 | ADORA3 (0.40) | ADORA3ARF6TRIM58NOS1NOS2 | |
| SCHEMBL6838083 | 0.89 | ADORA3 (0.36) | ADORA3TRIM58HRH1NOS1NOS2 | |
| SCHEMBL6839979 | 0.89 | ADRB2 (0.35) | ADORA3ARF6ALOX5APTLR7ADRB2 | |
| SCHEMBL6838584 | 0.88 | ADORA3 (0.39) | ADORA3ARF6NOS1NOS2SOS1 | |
| SCHEMBL6840039 | 0.88 | ADRB2 (0.36) | ADORA3ARF6ALOX5APTLR7ADRB2 | |
| SCHEMBL6833712 | 0.87 | ADORA3 (0.46) | ADORA3TLR7HRH1RXRARXRB | |
| SCHEMBL6837680 | 0.87 | ADORA3 (0.34) | ADORA3ARF6ALOX5APTLR7HRH1 | |
| SCHEMBL6838758 | 0.86 | ADORA3 (0.45) | ADORA3TLR7ADRB2HRH1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | IL2, IL1A, IL4 | ADORA3 3201/4885ARF6 2504/4885TRIM58 3947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.