Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTC4S | Q16873 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 14/20 | 0.60 |
| ▸ | RAB9A | P51151 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.58 |
| ▸ | NPC1 | O15118 | 2/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 3/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.51 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7074252 | 0.86 | SMN1; SMN2 (0.69) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL30733304 | 0.86 | SMN1; SMN2 (0.69) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL6847881 | 0.83 | ALDH1A1 (0.55) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL6950122 | 0.81 | ALDH1A1 (0.67) | ALDH1A1RAB9AMAPTALOX12NPC1 | |
| SCHEMBL7224530 | 0.80 | LTC4S (0.87) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL6847403 | 0.77 | LTC4S (1.00) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL5888407 | 0.76 | LTC4S (0.79) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL7220245 | 0.76 | LTC4S (0.79) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL5888522 | 0.76 | LTC4S (0.79) | LTC4SALDH1A1RAB9AMAPTALOX12 | |
| SCHEMBL13885949 | 0.76 | ALDH1A1 (0.68) | LTC4SALDH1A1RAB9AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | claimed |
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | PARKER HUGHES INSTITUTE | 2004-09-02 | — | — | US | disclosed |
| US-6774139-B1 | CONTRACEPTIVES | PARKER HUGHES INSTITUTE | 2004-08-10 | — | — | US | disclosed |
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | PARKER HUGHES INSTITUTE | 2003-07-03 | — | — | US | disclosed |
| US-6469034-B1 | TREATMENT OF HIV INFECTION, INCLUDING MUTANT, DRUG-SENSITIVE, DRUG- RESISTANT, AND MULTI-DRUG RESISTANT STRAINS | PARKER HUGHES INSTITUTE | 2002-10-22 | — | — | US | disclosed |
| EP-1194149-A1 | CYCLOHEXENYL-ETHYL-THIOUREA COMPOUNDS AND USE | Parker Hughes Institute (US) | 2002-04-10 | — | — | EP | disclosed |
| WO-2000078315-A1 | CYCLOHEXENYL-ETHYL-THIOUREA COMPOUNDS AND USE | PARKER HUGHES INSTITUTE (US) | 2000-12-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030125331-A1 | Cyclohexenyl-ethyl-thiourea compounds and use | TPMT, DNTT, BHMT | LTC4S 1637/4885ALDH1A1 3359/4885RAB9A 3078/4885 |
| US-20040171652-A1 | Antiviral and spermicidal contraceptives; 2-thiourea pyridinyl derivative containing compositions | ZP1, NASP, SAMHD1 | LTC4S 1340/4885ALDH1A1 1417/4885RAB9A 4098/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.