Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 5/20 | 0.53 |
| ▸ | FLT4 | P35916 | 5/20 | 0.53 |
| ▸ | KDR | P35968 | 5/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | AHR | P35869 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7794431 | 0.85 | MEN1 (0.58) | FLT1FLT4KDRHPGDLMNA | |
| SCHEMBL5958915 | 0.74 | FLT1 (0.76) | FLT1FLT4KDRLMNAMAPT | |
| SCHEMBL8661710 | 0.73 | FLT1 (0.74) | FLT1FLT4KDRHPGDLMNA | |
| SCHEMBL9815588 | 0.72 | CA2 (0.59) | FLT1FLT4KDRHPGDKMT2A | |
| SCHEMBL3675717 | 0.72 | NPC1 (0.70) | HPGDL3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL8654939 | 0.72 | FLT1 (0.76) | FLT1FLT4KDRHPGDLMNA | |
| SCHEMBL7743287 | 0.71 | MAPT (0.68) | LMNAL3MBTL1MAPTKMT2AMEN1 | |
| SCHEMBL22769031 | 0.71 | EPHX2 (0.47) | HPGDLMNAL3MBTL1MAPTPKM | |
| SCHEMBL5958982 | 0.71 | FLT1 (0.83) | FLT1FLT4KDRMAPTNPC1 | |
| SCHEMBL23909567 | 0.71 | FLT1 (0.85) | FLT1FLT4KDRHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171079-A1 | Combinatorial active compound synthesis and its intermediates | HAAF KLAUS (DE) | 2004-09-02 | — | — | US | disclosed |
| US-20030158443-A1 | Combinatorial active compound synthesis and its intermediates | HAAF KLAUS (DE) | 2003-08-21 | — | — | US | disclosed |
| EP-0837056-B1 | Combinatorial reagent synthesis and intermediates therefor | BAYER CROPSCIENCE GMBH (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020128383-A1 | COMBINATORIAL ACTIVE COMPOUND SYNTHESIS AND ITS INTERMEDIATES | HOECHST SCHERING AGREVO GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
| EP-0837056-A2 | Combinatorial reagent synthesis and intermediates therefor | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171079-A1 | Combinatorial active compound synthesis and its intermediates | NCL, POLR2E, NOC2L | FLT1 3109/4885FLT4 3780/4885KDR 4030/4885 |
| US-20030158443-A1 | Combinatorial active compound synthesis and its intermediates | NCL, POLR2E, COASY | FLT1 3121/4885FLT4 3931/4885KDR 4103/4885 |
| US-20020128383-A1 | COMBINATORIAL ACTIVE COMPOUND SYNTHESIS AND ITS INTERMEDIATES | NCL, POLR2E, NOC2L | FLT1 3107/4885FLT4 3798/4885KDR 4058/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.