Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 2/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6833915 | 0.91 | MTNR1A (0.39) | MTNR1AMTNR1BHTTL3MBTL1TACR1 | |
| SCHEMBL6838145 | 0.90 | MTNR1A (0.39) | MTNR1AMTNR1BHTTL3MBTL1TACR1 | |
| SCHEMBL6833826 | 0.90 | AVPR1B (0.39) | MTNR1AMTNR1BHTTL3MBTL1TACR1 | |
| SCHEMBL6838095 | 0.90 | MTNR1A (0.50) | MTNR1AMTNR1BL3MBTL1TACR1TLR7 | |
| SCHEMBL6837751 | 0.87 | CYP3A4 (0.37) | HTTL3MBTL1CYP2C9CYP2C19CYP1A2 | |
| Fumaric Acid SCHEMBL6838681 | 0.86 | MTNR1A (0.37) | MTNR1AMTNR1BHTTL3MBTL1TACR1 | |
| Fumaric Acid SCHEMBL6838685 | 0.86 | MTNR1A (0.37) | MTNR1AMTNR1BHTTL3MBTL1TACR1 | |
| SCHEMBL6834007 | 0.86 | LMNA (0.42) | MTNR1AMTNR1BHTTL3MBTL1RAB9A | |
| SCHEMBL6833799 | 0.82 | TLR7 (0.46) | MTNR1AMTNR1BHTTTACR1RAB9A | |
| SCHEMBL6837676 | 0.79 | EGFR (0.42) | RAB9ATLR7EGFRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | HOKURIKU SEIYAKU CO., LTD. (JP) | 2004-03-18 | — | — | US | disclosed |
| EP-1256582-A1 | 1H-IMIDAZOPYRIDINE DERIVATIVES | HOKURIKU SEIYAKU CO., LTD. (JP) | 2002-11-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040054182-A1 | 1h-imidazopyridine derivatives | IL2, IL1A, IL4 | MTNR1A 1161/4885MTNR1B 1342/4885HTT 4393/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.