Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.32 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.32 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.32 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.32 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.32 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.32 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
| ▸ | PLAT | P00750 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7872058 | 0.92 | P2RX7 (0.40) | GAASMN1; SMN2P2RX7EPHX2 | |
| SCHEMBL7673905 | 0.88 | GAA (0.33) | GAASMN1; SMN2ALDH1A1PSEN1PSEN2 | |
| SCHEMBL8907784 | 0.85 | P2RX7 (0.34) | GAAMAPTP2RX7FFAR4EPHX2 | |
| SCHEMBL5929427 | 0.84 | P2RX7 (0.39) | POLBGAASMN1; SMN2P2RX7PSEN1 | |
| SCHEMBL8654342 | 0.83 | P2RX7 (0.36) | GAASMN1; SMN2P2RX7PSEN1PSEN2 | |
| SCHEMBL5492364 | 0.83 | OPRM1 (0.34) | POLBTSHRGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7964600 | 0.80 | LPAR1 (0.33) | HPGDP2RX7FFAR4 | |
| SCHEMBL8907152 | 0.80 | P2RX7 (0.36) | POLBGAAMAPTP2RX7FFAR4 | |
| SCHEMBL7132879 | 0.79 | MAPK1 (0.37) | POLBTSHRGAASMN1; SMN2HPGD | |
| SCHEMBL8907272 | 0.79 | ADCY8 (0.40) | ALDH1A1MAPTP2RX7L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759548-B2 | PESTICIDES AND HERBICIDES. PHENYL-SUBSTITUTED CYCLIC KETOENOLS, A PLURALITY OF PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-06 | — | — | US | disclosed |
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | FISCHER REINER (DE) | 2003-07-31 | — | — | US | disclosed |
| US-6469196-B2 | PESTICIDES AND WEEDKILLERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | FISCHER REINER (DE) | 2002-02-21 | — | — | US | disclosed |
| US-6251830-B1 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| US-5994274-A | Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | DDT, CYP8B1, CYP1A1 | POLB 2504/4885TSHR 1710/4885GAA 782/4885 |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | DDT, CYP2E1, CYP8B1 | POLB 2671/4885TSHR 1183/4885GAA 785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.