Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
| ▸ | CA7 | P43166 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18486629 | 0.86 | MEN1 (0.61) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL21319337 | 0.83 | NPSR1 (0.42) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL16974734 | 0.79 | MEN1 (0.44) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL31482562 | 0.78 | KMT2A (0.54) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL3890445 | 0.78 | KMT2A (0.54) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL4455340 | 0.78 | MEN1 (0.54) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL9177686 | 0.78 | MEN1 (0.50) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL21319400 | 0.78 | CA1 (0.37) | MEN1KMT2APOLBCA12CA1 | |
| SCHEMBL780087 | 0.77 | MEN1 (0.53) | MEN1KMT2APOLBNPSR1KCNH2 | |
| SCHEMBL641441 | 0.77 | MEN1 (0.53) | MEN1KMT2APOLBNPSR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | claimed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | claimed |
| US-20040138487-A1 | Bisphospholane ligands with metals for hydrogenation catalysts for enantiomorphs | HOGE GARRETT STEWART | 2004-07-15 | — | — | US | claimed |
| US-20030073868-A1 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER-LAMBERT COMPANY | 2003-04-17 | — | — | US | claimed |
| US-20020143214-A1 | Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | HOGE GARRETT STEWART (US) | 2002-10-03 | — | — | US | claimed |
| CN-116854631-B | 4-Aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2025-04-15 | — | — | CN | disclosed |
| CN-116854631-A | 4-aryl-2-pyridone compound and preparation method thereof | 安徽中医药大学 | 2023-10-10 | — | — | CN | disclosed |
| US-7414156-B2 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER LAMBERT CO. (US) | 2008-08-19 | — | — | US | disclosed |
| US-7414156-B2 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | WARNER LAMBERT CO. (US) | 2008-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020143214-A1 | Synthesis of non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | PHOSPHO1, PPIP5K2, PFKFB2 | MEN1 94/4885KMT2A 3175/4885POLB 2077/4885 |
| US-20030073868-A1 | Non-C2-symmetric bisphosphine ligands as catalysts for asymmetric hydrogenation | PHOSPHO1, PPIP5K2, DNM2 | MEN1 68/4885KMT2A 2844/4885POLB 1963/4885 |
| US-20040138487-A1 | Bisphospholane ligands with metals for hydrogenation catalysts for enantiomorphs | BPGM, PHOSPHO1, PPIP5K2 | MEN1 190/4885KMT2A 3539/4885POLB 1970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.