Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.53 |
| ▸ | MAPT | P10636 | 10/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.53 |
| ▸ | MEN1 | O00255 | 8/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1930658 | 0.78 | TRPA1 (0.47) | TRPA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL13485323 | 0.78 | MAPT (0.54) | TRPA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL2726862 | 0.78 | TRPA1 (0.72) | TRPA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL29404696 | 0.77 | TRPA1 (1.00) | TRPA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL436060 | 0.77 | TRPA1 (1.00) | TRPA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL1722125 | 0.75 | KDM4E (0.55) | ALDH1A1KMT2AKDM4ELMNACISD1 | |
| SCHEMBL4659964 | 0.75 | KDM4E (0.55) | ALDH1A1KMT2AKDM4ELMNACISD1 | |
| SCHEMBL1722127 | 0.75 | KDM4E (0.55) | ALDH1A1KMT2AKDM4ELMNACISD1 | |
| SCHEMBL11313178 | 0.73 | KMT2A (0.52) | TRPA1ALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL4656018 | 0.71 | ALDH1A1 (0.43) | TRPA1ALDH1A1MAPTKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2004-07-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040142821-A1 | Pesticide composition comprising malononitrile compounds | CBR1, CBR3, ME1 | TRPA1 1382/4885ALDH1A1 867/4885MAPT 4249/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.