Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 5/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.44 |
| ▸ | MC3R | P41968 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.44 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.44 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Caffeine SCHEMBL18152858 | 0.83 | ADORA2B (0.56) | ADORA2BALOX15TP53RXFP1ALDH1A1 | |
| SCHEMBL684044 | 0.82 | ADORA2B (0.49) | ADORA2BALOX15RXFP1ALDH1A1LMNA | |
| Caffeine SCHEMBL10345108 | 0.79 | ADORA2B (0.50) | ADORA2BALOX15TP53RXFP1ALDH1A1 | |
| SCHEMBL684090 | 0.78 | ADORA2B (0.54) | ADORA2BRXFP1ALDH1A1LMNATSHR | |
| SCHEMBL11702624 | 0.76 | ADORA2B (0.57) | ADORA2BTP53RXFP1ALDH1A1LMNA | |
| Etamiphyllin SCHEMBL10386653 | 0.76 | ADORA2B (0.52) | ADORA2BALOX15TP53RXFP1ALDH1A1 | |
| Benorilate SCHEMBL17558524 | 0.74 | HSD17B10 (0.46) | ADORA2BALOX15TP53RXFP1ALDH1A1 | |
| SCHEMBL684042 | 0.74 | ADORA2B (0.51) | ADORA2BTP53RXFP1ALDH1A1LMNA | |
| SCHEMBL5471122 | 0.74 | ADORA2B (0.62) | ADORA2BRXFP1LMNAPIK3CDPOLB | |
| Caffeine SCHEMBL4063268 | 0.74 | RXFP1 (0.44) | ADORA2BALOX15TP53RXFP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3935196-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1976-01-27 | — | — | US | claimed |
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
| US-4002756-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1977-01-11 | — | — | US | disclosed |
| US-4000132-A | REACTION WITH CARBOXYLIC ACID, PHOSGENE, OR THIONYL CHLORIDE | INTERX RESEARCH CORPORATION (US) | 1976-12-28 | — | — | US | disclosed |
| US-3935196-A | Useful pro-drug forms of theophylline | INTERX RESEARCH CORPORATION (US) | 1976-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | ADORA2B 786/4885ALOX15 1046/4885TP53 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.