Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 1/20 | 0.57 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 3/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL683376 | 0.94 | AGTR2 (0.51) | AGTR2AGTR1PPARG | |
| SCHEMBL684052 | 0.93 | AGTR2 (0.60) | AGTR2AGTR1PPARGKCNH2 | |
| SCHEMBL12894783 | 0.92 | AGTR1 (0.50) | AGTR1PPARG | |
| SCHEMBL7014349 | 0.87 | AGTR1 (0.45) | AGTR2AGTR1PPARG | |
| SCHEMBL683670 | 0.87 | AGTR1 (0.49) | AGTR1PPARG | |
| SCHEMBL684058 | 0.87 | AGTR1 (0.49) | AGTR1PPARG | |
| SCHEMBL683658 | 0.86 | AGTR2 (0.75) | AGTR2AGTR1PPARGKCNH2 | |
| SCHEMBL7015555 | 0.85 | AGTR1 (0.45) | AGTR2AGTR1PPARG | |
| SCHEMBL7014422 | 0.85 | AGTR1 (0.45) | AGTR2AGTR1PPARG | |
| SCHEMBL12477022 | 0.85 | AGTR2 (0.59) | AGTR2AGTR1PPARGKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | BRAINCELLS INC. (US) | 2011-11-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110269717-A1 | NEUROGENESIS BY MODULATING ANGIOTENSIN | NGF, DCX, BDNF | AGTR2 9/4885AGTR1 8/4885PPARG 622/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.