Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | TSHR | P16473 | 3/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.44 |
| ▸ | CA1 | P00915 | 4/20 | 0.43 |
| ▸ | CA2 | P00918 | 4/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA3 | P07451 | 2/20 | 0.43 |
| ▸ | CA6 | P23280 | 2/20 | 0.43 |
| ▸ | CA5A | P35218 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.43 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.43 |
| ▸ | TYR | P14679 | 1/20 | 0.43 |
| ▸ | DRD1 | P21728 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1021140 | 0.85 | HTT (0.59) | HTTTSHRTP53KMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL28509987 | 0.79 | TSHR (0.71) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL338413 | 0.79 | TSHR (0.71) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL4243136 | 0.79 | TSHR (0.71) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL6476384 | 0.79 | HTT (0.67) | HTTTSHRTP53KMT2AALDH1A1 | |
| SCHEMBL3465503 | 0.77 | HTT (0.56) | HTTTSHRTP53KMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL27832014 | 0.77 | TSHR (0.67) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL9018820 | 0.77 | HTT (0.55) | HTTTSHRTP53ALDH1A1SMN1; SMN2 | |
| SCHEMBL2283560 | 0.77 | HTT (0.55) | HTTTSHRTP53KMT2AALDH1A1 | |
| Terephthalic Acid SCHEMBL23071346 | 0.77 | TSHR (0.75) | TSHRTP53KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171079-A1 | Combinatorial active compound synthesis and its intermediates | HAAF KLAUS (DE) | 2004-09-02 | — | — | US | disclosed |
| US-20030158443-A1 | Combinatorial active compound synthesis and its intermediates | HAAF KLAUS (DE) | 2003-08-21 | — | — | US | disclosed |
| EP-0837056-B1 | Combinatorial reagent synthesis and intermediates therefor | BAYER CROPSCIENCE GMBH (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-20020128383-A1 | COMBINATORIAL ACTIVE COMPOUND SYNTHESIS AND ITS INTERMEDIATES | HOECHST SCHERING AGREVO GMBH (DE) | 2002-09-12 | — | — | US | disclosed |
| EP-0837056-A2 | Combinatorial reagent synthesis and intermediates therefor | Hoechst Schering AgrEvo GmbH (DE) | 1998-04-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171079-A1 | Combinatorial active compound synthesis and its intermediates | NCL, POLR2E, NOC2L | HTT 2081/4885TSHR 3718/4885TP53 4491/4885 |
| US-20030158443-A1 | Combinatorial active compound synthesis and its intermediates | NCL, POLR2E, COASY | HTT 2072/4885TSHR 3823/4885TP53 4528/4885 |
| US-20020128383-A1 | COMBINATORIAL ACTIVE COMPOUND SYNTHESIS AND ITS INTERMEDIATES | NCL, POLR2E, NOC2L | HTT 2055/4885TSHR 3781/4885TP53 4463/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.