Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.34 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.34 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.34 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methane SCHEMBL3419162 | 0.97 | ALDH1A1 (0.39) | ALDH1A1CHRNA7TSHRMAPTSMN1; SMN2 | |
| SCHEMBL27638822 | 0.91 | ALDH1A1 (0.35) | ALDH1A1CHRNA7TSHRMAPTSMN1; SMN2 | |
| Trimethylammonium SCHEMBL31097229 | 0.82 | — | — | |
| SCHEMBL22520619 | 0.82 | ACHE (0.40) | ALDH1A1SMN1; SMN2KDM4ESIGMAR1 | |
| SCHEMBL2925203 | 0.79 | DRD2 (0.41) | KDM4EGAASIGMAR1 | |
| SCHEMBL22307131 | 0.79 | TSHR (0.39) | TSHRSMN1; SMN2KDM4EGAA | |
| SCHEMBL84808 | 0.78 | CHRNA7 (0.48) | ALDH1A1CHRNA7MAPTSMN1; SMN2KDM4E | |
| SCHEMBL577415 | 0.78 | CHRNA7 (0.48) | ALDH1A1CHRNA7MAPTSMN1; SMN2KDM4E | |
| SCHEMBL6657817 | 0.78 | CHRNA7 (0.48) | ALDH1A1CHRNA7MAPTSMN1; SMN2KDM4E | |
| SCHEMBL577052 | 0.78 | CHRNA7 (0.48) | ALDH1A1CHRNA7MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4380572-B1 | FORMULATION FOR SUBSTITUTED 2-AMINOTHIAZOLES IN THE TREATMENT OF FUNGAL AND FUNGAL-BACTERIAL INFECTIONS OF THE NAIL | ONYCHOPHARM GMBH (DE) | 2025-10-01 | — | — | EP | disclosed |
| EP-4380572-A1 | FORMULATION FOR SUBSTITUTED 2-AMINOTHIAZOLES IN THE TREATMENT OF FUNGAL AND FUNGAL-BACTERIAL INFECTIONS OF THE NAIL | OnychoPharm GmbH (DE) | 2024-06-12 | — | — | EP | disclosed |
| WO-2023011750-A1 | FORMULATION FOR SUBSTITUTED 2-AMINOTHIAZOLES IN THE TREATMENT OF FUNGAL AND FUNGAL-BACTERIAL INFECTIONS OF THE NAIL | ONYCHOPHARM GMBH (DE) | 2023-02-09 | — | — | WO | disclosed |
| EP-4129292-A1 | FORMULATION FOR SUBSTITUTED 2-AMINOTHIAZOLES IN THE TREATMENT OF FUNGAL AND FUNGAL-BACTERIAL INFECTIONS OF THE NAIL | OnychoPharm GmbH (DE) | 2023-02-08 | — | — | EP | disclosed |
| EP-3448386-B1 | ISOQUINOLIN-3-YL CARBOXAMIDES AND PREPARATION AND USE THEREOF | SAMUMED LLC (US) | 2021-03-03 | — | — | EP | disclosed |
| EP-2831067-B1 | SMALL MOLECULE INHIBITORS OF MCL-1 AND USES THEREOF | UNIV MICHIGAN REGENTS (US) | 2017-11-01 | — | — | EP | disclosed |
| US-9393218-B2 | Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and patches that contain these polymers | EPINAMICS GMBH (DE) | 2016-07-19 | — | — | US | disclosed |
| US-8063050-B2 | Hydroxylated and methoxylated pyrimidyl cyclopentanes as AKT protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2011-11-22 | — | — | US | disclosed |
| EP-1962815-B1 | USE OF FILM-FORMING HAIR-CARE POLYMERS FROM THE GROUP OF POLYURETHANES AND PHARMACEUTICAL PREPARATIONS AND PLASTERS CONTAINING SAID POLYMERS | EPINAMICS GMBH (DE) | 2010-08-11 | — | — | EP | disclosed |
| EP-1962815-A1 | USE OF FILM-FORMING HAIR-CARE POLYMERS FROM THE GROUP OF POLYURETHANES AND PHARMACEUTICAL PREPARATIONS AND PLASTERS CONTAINING SAID POLYMERS | Epinamics GmbH (DE) | 2008-09-03 | — | — | EP | disclosed |
| US-20080051399-A1 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA INC. | 2008-02-28 | — | — | US | disclosed |
| US-20070248658-A1 | Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and patches that contain these polymers | EPINAMICS GMBH (DE) | 2007-10-25 | — | — | US | disclosed |
| WO-2007077029-A1 | USE OF FILM-FORMING HAIR-CARE POLYMERS FROM THE GROUP OF POLYURETHANES AND PHARMACEUTICAL PREPARATIONS AND PLASTERS CONTAINING SAID POLYMERS | EPINAMICS GMBH (DE) | 2007-07-12 | — | — | WO | disclosed |
| EP-1800671-A1 | Use of film-forming hair care polymers and pharmaceutical preparations and patches comprising such polymers | Bayer Schering Pharma Aktiengesellschaft (DE) | 2007-06-27 | — | — | EP | disclosed |
| US-7141647-B2 | Image file arrangement for use with an improved image quality assurance system | KABUSHIKI KAISHA TOSHIBA (JP) | 2006-11-28 | — | — | US | disclosed |
| US-20050020701-A1 | Method of treating waste product containing flexible polyurethane resin | KABUSHIKI KAISHA TOSHIBA (JP) | 2005-01-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080051399-A1 | HYDROXYLATED AND METHOXYLATED PYRIMIDYL CYCLOPENTANES AS AKT PROTEIN KINASE INHIBITORS | AKT1, AKT2, AKT1S1 | ALDH1A1 1715/4885CHRNA7 4875/4885TSHR 4108/4885 |
| US-20070248658-A1 | Use of film-forming hair care polymers from the group of polyurethanes and pharmaceutical preparations and patches that contain these polymers | CUTA, PUF60, TET3 | ALDH1A1 1133/4885CHRNA7 3071/4885TSHR 3647/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.