Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1537457 | 0.91 | XDH (0.41) | XDHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL8794058 | 0.87 | TAS1R3 (0.39) | SMN1; SMN2ALDH1A1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL6834732 | 0.81 | HTT (0.42) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL6839567 | 0.80 | ALDH1A1 (0.37) | XDHSMN1; SMN2ALDH1A1MEN1KMT2A | |
| SCHEMBL6841189 | 0.80 | MAPT (0.39) | ALDH1A1MEN1KMT2ATAS1R3TAS1R1 | |
| SCHEMBL15757000 | 0.79 | TAS1R3 (0.36) | SMN1; SMN2ALDH1A1TAS1R3TAS1R1KDM4E | |
| SCHEMBL8795536 | 0.74 | NLRP3 (0.44) | SMN1; SMN2ALDH1A1MEN1KMT2ATDP1 | |
| SCHEMBL7486568 | 0.74 | MAPK1 (0.43) | SMN1; SMN2ALDH1A1MEN1KMT2ATAS1R3 | |
| SCHEMBL3163620 | 0.73 | TAS1R3 (0.34) | SMN1; SMN2ALDH1A1MEN1KMT2ATAS1R3 | |
| SCHEMBL16207545 | 0.72 | SMN1; SMN2 (0.40) | XDHSMN1; SMN2ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6759548-B2 | PESTICIDES AND HERBICIDES. PHENYL-SUBSTITUTED CYCLIC KETOENOLS, A PLURALITY OF PROCESSES AND INTERMEDIATES FOR THEIR PREPARATION | BAYER AKTIENGESELLSCHAFT (DE) | 2004-07-06 | — | — | US | disclosed |
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | FISCHER REINER (DE) | 2003-07-31 | — | — | US | disclosed |
| EP-0835243-B1 | DIALKYL PHENYL HALIDE-SUBSTITUTED KETO-ENOLS FOR USE AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6469196-B2 | PESTICIDES AND WEEDKILLERS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | FISCHER REINER (DE) | 2002-02-21 | — | — | US | disclosed |
| US-6251830-B1 | PESTICIDES AND HERBICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-06-26 | — | — | US | disclosed |
| US-5994274-A | Dialkyl phenyl halide-substituted keto-enols for use as herbicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1999-11-30 | — | — | US | disclosed |
| EP-0835243-A1 | DIALKYL PHENYL HALIDE-SUBSTITUTED KETO-ENOLS FOR USE AS HERBICIDES AND PESTICIDES | BAYER AG (DE) | 1998-04-15 | — | — | EP | disclosed |
| WO-1997002243-A1 | DIALKYL PHENYL HALIDE-SUBSTITUTED KETO-ENOLS FOR USE AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-01-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030144504-A1 | Pesticides and herbicides. phenyl-substituted cyclic ketoenols, a plurality of processes and intermediates for their preparation | DDT, CYP8B1, CYP1A1 | XDH 607/4885SMN1; SMN2 4665/4885ALDH1A1 566/4885 |
| US-20020022575-A1 | Dialkyl-halogenophenyl-substituted ketoenols | DDT, CYP2E1, CYP8B1 | XDH 323/4885SMN1; SMN2 4638/4885ALDH1A1 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.