Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 4/20 | 0.52 |
| ▸ | CA2 | P00918 | 4/20 | 0.52 |
| ▸ | CA9 | Q16790 | 4/20 | 0.52 |
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CASP3 | P42574 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP4 | P49662 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | CASP9 | P55211 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.51 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31687464 | 0.88 | ALDH1A1 (0.73) | ALDH1A1HTTHPGDCA12CA2 | |
| SCHEMBL2049541 | 0.88 | ALDH1A1 (0.73) | ALDH1A1HTTHPGDCA12CA2 | |
| SCHEMBL1832812 | 0.85 | CA12 (0.60) | CA12CA2CA9CA1CASP3 | |
| SCHEMBL17029125 | 0.80 | CASP3 (0.66) | ALDH1A1HTTHPGDCA12CA2 | |
| SCHEMBL21176664 | 0.80 | CA12 (0.70) | HPGDCA12CA2CA9CA1 | |
| SCHEMBL2567466 | 0.79 | ALDH1A1 (0.55) | ALDH1A1HTTHPGDCA12CA2 | |
| SCHEMBL7073273 | 0.78 | KMT2A (0.51) | ALDH1A1HTTHPGDCA12CA2 | |
| SCHEMBL6675322 | 0.78 | KDM4E (0.59) | ALDH1A1HTTHPGDCA12CA2 | |
| SCHEMBL3856490 | 0.77 | CA12 (0.76) | HTTCA12CA2CA9CA1 | |
| SCHEMBL16744038 | 0.76 | KMT2A (0.56) | ALDH1A1HTTHPGDCA12CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9006459-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2015-04-14 | — | — | US | disclosed |
| US-9006459-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2015-04-14 | — | — | US | disclosed |
| US-9006459-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2015-04-14 | — | — | US | disclosed |
| US-20150004712-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITY OF OTTAWA (CA) | 2015-01-01 | — | — | US | disclosed |
| US-20150004712-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITY OF OTTAWA (CA) | 2015-01-01 | — | — | US | disclosed |
| US-20150004712-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITY OF OTTAWA (CA) | 2015-01-01 | — | — | US | disclosed |
| US-8835641-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2014-09-16 | — | — | US | disclosed |
| US-8835641-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2014-09-16 | — | — | US | disclosed |
| US-8835641-B2 | Fluorescent markers and use thereof for labeling specific protein targets | UNIVERSITY OF OTTAWA (CA) | 2014-09-16 | — | — | US | disclosed |
| US-20120171665-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITE DE MONTREAL (CA) | 2012-07-05 | — | — | US | disclosed |
| US-20120171665-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITE DE MONTREAL (CA) | 2012-07-05 | — | — | US | disclosed |
| US-20120171665-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | UNIVERSITE DE MONTREAL (CA) | 2012-07-05 | — | — | US | disclosed |
| US-20040157919-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | WU YONG-QIAN (US) | 2004-08-12 | — | — | US | disclosed |
| US-6656971-B2 | Non-peptidic small organic compounds having an affinity for cyclophilin (CyP)-type immunophilins; inhibiting their peptidyl-prolyl isomerase activity; treating variety of medical conditions | GUILFORD PHARMACEUTICALS INC. | 2003-12-02 | — | — | US | disclosed |
| EP-1360173-A2 | TRISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIR USE | GUILFORD PHARMACEUTICALS INC. (US) | 2003-11-12 | — | — | EP | disclosed |
| US-20020165275-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | GUILFORD PHARMACEUTICALS INC. | 2002-11-07 | — | — | US | disclosed |
| WO-2002059080-A2 | TRISUBSTITUTED CARBOCYCLIC CYCLOPHILIN BINDING COMPOUNDS AND THEIR USE | GUILFORD PHARMACEUTICALS INC. (US) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120171665-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | HNRNPH1, HNRNPH3, HNRNPC | ALDH1A1 2633/4885HTT 2402/4885HPGD 1817/4885 |
| US-20040157919-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | FKBP2, PPIG, FKBP8 | ALDH1A1 2070/4885HTT 2932/4885HPGD 384/4885 |
| US-20150004712-A1 | FLUORESCENT MARKERS AND USE THEREOF FOR LABELING SPECIFIC PROTEIN TARGETS | HNRNPH1, HNRNPH3, HNRNPC | ALDH1A1 2633/4885HTT 2402/4885HPGD 1817/4885 |
| US-20020165275-A1 | Trisubstituted carbocyclic cyclophilin binding compounds and their use | FKBP2, PPIG, FKBP8 | ALDH1A1 2070/4885HTT 2932/4885HPGD 384/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.