SCHEMBL6841739

SCHEMBL6841739

O[Si](O)(CCCCl)c1ccccc1

nearest known ligand 0.32

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 1/20 0.32
GLA P06280 1/20 0.32
GAA P10253 1/20 0.32
TRPA1 O75762 1/20 0.31
MAPK1 P28482 1/20 0.31
GSK3B P49841 1/20 0.31
HIF1A Q16665 1/20 0.31
SLC9A1 P19634 1/20 0.31
ESR1 P03372 1/20 0.30
ESR2 Q92731 1/20 0.30
MAPT P10636 1/20 0.30
CASP3 P42574 1/20 0.30
RAB9A P51151 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
SENP8 Q96LD8 1/20 0.30
SENP7 Q9BQF6 1/20 0.30
SENP6 Q9GZR1 1/20 0.30
KCNA3 P22001 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272398 0.78 PCSK9 (0.39) ALDH1A1
SCHEMBL4533823 0.78 MAOA (0.40)
SCHEMBL3230668 0.77 KDM4E (0.33) ALDH1A1KDM4EGLAGAASLC9A1
SCHEMBL4271660 0.76 SLC9A1 (0.32) SLC9A1KCNA3
SCHEMBL8908265 0.76 SLC9A1 (0.32) SLC9A1ESR1ESR2KCNA3
SCHEMBL28743025 0.75 NAAA (0.43) ALDH1A1
SCHEMBL5807500 0.75 MAOA (0.47) MAPK1MAPT
SCHEMBL3228612 0.74 MGAM (0.43) SLC9A1ESR1ESR2MAPTKCNA3
SCHEMBL3238058 0.74 ESR1 (0.34) SLC9A1ESR1ESR2MAPTKCNA3
SCHEMBL272865 0.73 ESR1 (0.37) ALDH1A1KDM4EGAAESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6764807-B2 LITHOGRAPHY KODAK POLYCHROME GRAPHICS LLC 2004-07-20 US disclosed
US-20020086235-A1 Lithography EASTMAN KODAK COMPANY 2002-07-04 US disclosed
US-6399271-B1 HYDROXY CONTAINING COMPOUND WITH AFFINITY FOR INK, AND TITANIUM OR SILICON CONTAINING COMPOUND WITH DIFFERENT AFFINITY FOR INK KODAK POLYCHROME GRAPHICS LLC 2002-06-04 US disclosed
EP-1021301-A1 PLANOGRAPHIC PRINTING Kodak Polychrome Graphics Company Ltd. (US) 2000-07-26 EP disclosed
WO-1999014048-A1 PLANOGRAPHIC PRINTING KODAK POLYCHROME GRAPHICS COMPANY LTD (US) 1999-03-25 WO disclosed
EP-0377175-A2 Pattern forming composition and process for forming pattern using the same HITACHI, LTD. (JP) 1990-07-11 EP disclosed