Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 15/20 | 0.64 |
| ▸ | DRD2 | P14416 | 14/20 | 0.64 |
| ▸ | DRD3 | P35462 | 14/20 | 0.64 |
| ▸ | DRD4 | P21917 | 8/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | HTR2B | P41595 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.49 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6841510 | 0.89 | OPRM1 (0.61) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6841504 | 0.89 | OPRM1 (0.66) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6841116 | 0.82 | OPRM1 (0.54) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6841125 | 0.82 | OPRM1 (0.73) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6841801 | 0.80 | OPRM1 (0.60) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6836914 | 0.79 | OPRM1 (0.69) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6843619 | 0.78 | OPRM1 (0.45) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6661040 | 0.78 | OPRM1 (0.61) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL6665100 | 0.77 | OPRM1 (0.60) | OPRM1DRD2DRD3DRD4MEN1 | |
| SCHEMBL29799805 | 0.77 | DRD2 (1.00) | OPRM1DRD2DRD3DRD4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | SSP CO., LTD. (JP) | 2004-02-19 | — | — | US | disclosed |
| EP-1325912-A1 | 2,2-DIPHENYLBUTANAMIDE DERIVATIVES AND MEDICINES CONTAINING THE SAME | SSP Co., Ltd. (JP) | 2003-07-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040034104-A1 | 2,2-Diphenylbutanamide derivatives and medicines containing the same | OPRD1, OPRM1, OPRK1 | OPRM1 2/4885DRD2 48/4885DRD3 95/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.