SCHEMBL29974237

SCHEMBL29974237

Cc1ccc(-c2nc(Cl)nc(-c3ccc(C)cc3C)n2)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 5/20 0.41
RAB9A P51151 5/20 0.41
MEN1 O00255 4/20 0.41
KMT2A Q03164 4/20 0.41
MAPT P10636 6/20 0.38
KDM4E B2RXH2 4/20 0.38
ALDH1A1 P00352 4/20 0.38
HPGD P15428 3/20 0.38
TDP1 Q9NUW8 3/20 0.38
TP53 P04637 3/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
GAA P10253 1/20 0.38
LMNA P02545 3/20 0.38
NPSR1 Q6W5P4 2/20 0.37
TSHR P16473 1/20 0.37
MAPK1 P28482 1/20 0.37
NFKB1 P19838 1/20 0.36
CYP1A2 P05177 2/20 0.36
CYP2A6 P11509 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1245251 1.00 NPC1 (0.41) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL6842063 1.00 NPC1 (0.41) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL4210497 0.96 NPC1 (0.41) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL29973207 0.96 NPC1 (0.41) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL4210533 0.91 KDM4E (0.44) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL29354045 0.89 NPC1 (0.47) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL1245257 0.89 NPC1 (0.47) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL4209528 0.87 ESR2 (0.43) MEN1KMT2AMAPTTDP1TP53
SCHEMBL16019276 0.83 NPC1 (0.44) NPC1RAB9AMEN1KMT2AMAPT
SCHEMBL4207319 0.82 NPC1 (0.38) NPC1RAB9AMEN1KMT2AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12319661-B2 Polycyclic compound EUTEC NEW MATERIALS TECHNOLOGY (SUZHOU) CO., LTD. (CN) 2025-06-03 US disclosed
CN-115745970-B Polycyclic compound, preparation method and membrane 江苏裕事达新材料科技有限责任公司 2024-12-13 CN disclosed
CN-118255725-A Preparation method of triazine compound 上海朗亿功能材料有限公司 2024-06-28 CN disclosed
CN-111285853-B Polycyclic compound 江苏裕事达新材料科技有限责任公司 2023-07-28 CN disclosed
CN-115745970-A Polycyclic compound, preparation method and film 江苏裕事达新材料科技有限责任公司 2023-03-07 CN disclosed
CN-109651275-B Triazine compound, composition and preparation method thereof 江苏裕事达新材料科技有限责任公司 2022-12-06 CN disclosed
EP-4081510-A1 TRIAZINE UV ABSORBERS AND A PROCESS FOR THE PREPARATION THEREOF BASF SE (DE) 2022-11-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12319661-B2 Polycyclic compound CUTA, CDH1, DSG1 NPC1 4112/4885RAB9A 3272/4885MEN1 485/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.