Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | SHBG | P04278 | 4/20 | 0.46 |
| ▸ | STS | P08842 | 6/20 | 0.45 |
| ▸ | ABCB11 | O95342 | 3/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.42 |
| ▸ | ESR1 | P03372 | 8/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | AR | P10275 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.40 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17525944 | 0.80 | SHBG (0.70) | AKR1C3SHBGSTSABCB11HSD17B1 | |
| SCHEMBL15973296 | 0.75 | STS (0.71) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL13951936 | 0.75 | STS (0.71) | SHBGSTSHSD17B1ESR1ESR2 | |
| SCHEMBL15973298 | 0.75 | AKR1C3 (0.53) | AKR1C3SHBGSTSABCB11HSD17B1 | |
| SCHEMBL14048667 | 0.74 | HSD17B10 (0.73) | SHBGSTSABCB11ESR1ESR2 | |
| SCHEMBL14048666 | 0.72 | LMNA (0.56) | AKR1C3SHBGSTSABCB11ESR1 | |
| SCHEMBL20006619 | 0.70 | AKR1C3 (0.56) | AKR1C3SHBGSTSABCB11HSD17B1 | |
| SCHEMBL6258256 | 0.69 | ESR1 (0.66) | SHBGSTSABCB11HSD17B1ESR1 | |
| SCHEMBL6260538 | 0.69 | ESR1 (0.66) | SHBGSTSABCB11HSD17B1ESR1 | |
| SCHEMBL20006567 | 0.69 | CYP17A1 (0.60) | AKR1C3ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040224935-A1 | Topical antiandrogenic steroids | ENDORECHERCHE, INC. | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040224935-A1 | Topical antiandrogenic steroids | CYP17A1, SRD5A1, SRD5A2 | AKR1C3 52/4885SHBG 20/4885STS 55/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.