Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 17/20 | 0.39 |
| ▸ | CTSL | P07711 | 16/20 | 0.39 |
| ▸ | CTSS | P25774 | 15/20 | 0.39 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6843710 | 0.87 | CTSK (0.51) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6843807 | 0.84 | CTSK (0.51) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6842269 | 0.81 | CTSK (0.54) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4623767 | 0.80 | CTSL (0.55) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4623775 | 0.80 | CTSL (0.55) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6836459 | 0.79 | CTSK (0.39) | CTSKCTSLCTSSSMYD3 | |
| SCHEMBL4624775 | 0.79 | CTSK (0.40) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4323935 | 0.78 | CTSK (0.43) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL4317772 | 0.78 | CTSK (0.43) | CTSKCTSLCTSSCTSVCTSB | |
| SCHEMBL6613825 | 0.78 | CTSK (0.39) | CTSKCTSLCTSSSMYD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040044201-A1 | Protease inhibitors | GLAXOSMITHKLINE LLC | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040044201-A1 | Protease inhibitors | CTSK, CTSE, CTSZ | CTSK 1/4885CTSL 11/4885CTSS 5/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.