Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | POLB | P06746 | 4/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.65 |
| ▸ | NPC1 | O15118 | 2/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.65 |
| ▸ | CASP3 | P42574 | 1/20 | 0.65 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.65 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.65 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.65 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.59 |
| ▸ | EIF4E | P06730 | 1/20 | 0.59 |
| ▸ | EIF4G1 | Q04637 | 1/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | RECQL | P46063 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL46215 | 0.89 | ENPP2 (0.75) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL29424240 | 0.83 | MEN1 (0.85) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL29883225 | 0.81 | KMT2A (0.83) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL16639749 | 0.81 | KMT2A (0.72) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL6392207 | 0.79 | MEN1 (0.87) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL6392210 | 0.79 | MEN1 (0.87) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL29468145 | 0.79 | KMT2A (0.75) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL29358417 | 0.79 | KMT2A (1.00) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL14507111 | 0.79 | MEN1 (0.69) | MEN1KMT2APOLBL3MBTL1NPC1 | |
| SCHEMBL29901272 | 0.78 | KMT2A (0.68) | MEN1KMT2APOLBL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010255-A1 | Compounds and Methods for Regulating Integrins | ATEGRIN, INC. | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010255-A1 | Compounds and Methods for Regulating Integrins | ITGB8, ITGB3, ITGAM | MEN1 1586/4885KMT2A 2448/4885POLB 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.