Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 11/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.34 |
| ▸ | WNT3A | P56704 | 1/20 | 0.34 |
| ▸ | NQO1 | P15559 | 2/20 | 0.32 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6217642 | 0.96 | MEN1 (0.38) | MMP13MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL6842318 | 0.87 | MMP13 (0.40) | MMP13MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL6838413 | 0.83 | NQO1 (0.36) | MMP13CTNNB1WNT3ANQO1FFAR1 | |
| SCHEMBL6194134 | 0.83 | MEN1 (0.40) | MMP13MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL6843025 | 0.83 | MEN1 (0.40) | MMP13MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL6212049 | 0.82 | MMP13 (0.42) | MMP13ALDH1A1NQO1SLC22A8FFAR1 | |
| SCHEMBL6210537 | 0.81 | MEN1 (0.42) | MMP13MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL6838414 | 0.80 | MMP13 (0.37) | MMP13NQO1SLC22A8FFAR1FFAR4 | |
| SCHEMBL6194013 | 0.80 | MMP13 (0.42) | MMP13MEN1ALDH1A1GAAKMT2A | |
| SCHEMBL6210633 | 0.80 | ABCB1 (0.35) | MMP13CTNNB1WNT3ANQO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | MMP13 3/4885MEN1 2172/4885ALDH1A1 1588/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.