Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO1 | P15559 | 2/20 | 0.36 |
| ▸ | MMP13 | P45452 | 7/20 | 0.35 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | HTR1B | P28222 | 4/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.33 |
| ▸ | CETP | P11597 | 1/20 | 0.33 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.32 |
| ▸ | WNT3A | P56704 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6210633 | 0.96 | ABCB1 (0.35) | NQO1MMP13IDO1HTR1BABCB1 | |
| SCHEMBL6214149 | 0.87 | CYP2A6 (0.35) | NQO1IDO1FFAR1FFAR4HTR1B | |
| SCHEMBL6843302 | 0.86 | — | — | |
| SCHEMBL6212049 | 0.85 | MMP13 (0.42) | NQO1MMP13FFAR1FFAR4 | |
| SCHEMBL6838414 | 0.85 | MMP13 (0.37) | NQO1MMP13FFAR1FFAR4CETP | |
| SCHEMBL6843282 | 0.83 | MMP13 (0.39) | NQO1MMP13FFAR1FFAR4CTNNB1 | |
| SCHEMBL6194302 | 0.82 | — | — | |
| SCHEMBL6214143 | 0.82 | ALOX5 (0.38) | IDO1FFAR1FFAR4HTR1BCTNNB1 | |
| SCHEMBL6212289 | 0.81 | MMP13 (0.38) | MMP13FFAR1FFAR4ABCB1 | |
| SCHEMBL6212222 | 0.81 | MMP13 (0.47) | MMP13FFAR1FFAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | LI JIE JACK (US) | 2004-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040043983-A1 | Naphthalene derivatives as matrix metalloproteinase inhibitors | MMP9, MMP8, MMP13 | NQO1 139/4885MMP13 3/4885IDO1 584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.