SCHEMBL6843822

SCHEMBL6843822

CC(C)c1ccc(C(O)C2CCCCN2)cc1

nearest known ligand 0.63

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A3 Q01959 13/20 0.63
SLC6A2 P23975 12/20 0.63
SLC6A4 P31645 12/20 0.63
HIF1A Q16665 1/20 0.62
HSD17B10 Q99714 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3164269 0.86 HIF1A (0.62) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL11408759 0.86 SLC6A2 (0.69) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL3184095 0.86 HIF1A (0.62) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL10327026 0.86 SLC6A3 (0.67) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL10326285 0.86 SLC6A3 (0.67) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL10326814 0.86 SLC6A3 (0.67) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL3164054 0.84 HIF1A (0.69) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL3172811 0.83 HIF1A (0.62) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL3174744 0.83 HIF1A (0.62) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10
SCHEMBL1794708 0.82 SLC6A3 (0.62) SLC6A3SLC6A2SLC6A4HIF1AHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040146542-A1 Non-therapeutical process for deterring vermin from warm-blooded animals, whereby 2-substituted-piperidine compound is is applied topically, together with a spreading additive, to the skin, the pelt or the plumage of the warm-blooded animal FROELICH OLIVIER 2004-07-29 US claimed
US-20020142023-A1 Composition for keeping away vermin NOVARTIS ANIMAL HEALTH US INC. 2002-10-03 US claimed
EP-1087662-B1 COMPOSITION FOR KEEPING AWAY VERMIN NOVARTIS AG (CH) 2002-04-10 EP claimed
US-20010003646-A1 Composition for keeping away vermin FROELICH OLIVIER (FR) 2001-06-14 US claimed
EP-1087662-A1 COMPOSITION FOR KEEPING AWAY VERMIN Novartis AG (CH) 2001-04-04 EP claimed
WO-1999065311-A1 COMPOSITION FOR KEEPING AWAY VERMIN NOVARTIS AG (CH) 1999-12-23 WO claimed
US-20040146542-A1 Non-therapeutical process for deterring vermin from warm-blooded animals, whereby 2-substituted-piperidine compound is is applied topically, together with a spreading additive, to the skin, the pelt or the plumage of the warm-blooded animal FROELICH OLIVIER 2004-07-29 US disclosed
US-20020142023-A1 Composition for keeping away vermin NOVARTIS ANIMAL HEALTH US INC. 2002-10-03 US disclosed
EP-1087662-B1 COMPOSITION FOR KEEPING AWAY VERMIN NOVARTIS AG (CH) 2002-04-10 EP disclosed
US-20010003646-A1 Composition for keeping away vermin FROELICH OLIVIER (FR) 2001-06-14 US disclosed
EP-1087662-A1 COMPOSITION FOR KEEPING AWAY VERMIN Novartis AG (CH) 2001-04-04 EP disclosed
WO-1999065311-A1 COMPOSITION FOR KEEPING AWAY VERMIN NOVARTIS AG (CH) 1999-12-23 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040146542-A1 Non-therapeutical process for deterring vermin from warm-blooded animals, whereby 2-substituted-piperidine compound is is applied topically, together with a spreading additive, to the skin, the pelt or the plumage of the warm-blooded animal PLG, PFN1, CUTA SLC6A3 1708/4885SLC6A2 661/4885SLC6A4 1605/4885
US-20010003646-A1 Composition for keeping away vermin VMP1, SERPINC1, VIL1 SLC6A3 1305/4885SLC6A2 895/4885SLC6A4 2177/4885
US-20020142023-A1 Composition for keeping away vermin VMP1, SERPINC1, VIL1 SLC6A3 1305/4885SLC6A2 895/4885SLC6A4 2177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.