Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.52 |
| ▸ | ALOX15B | O15296 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GSK3B | P49841 | 2/20 | 0.37 |
| ▸ | GSK3A | P49840 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.37 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.37 |
| ▸ | MLYCD | O95822 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14172954 | 0.81 | L3MBTL1 (0.57) | L3MBTL1ALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2945129 | 0.79 | MEN1 (0.53) | L3MBTL1RORCNR1H3MRGPRX4MAPT | |
| SCHEMBL24944902 | 0.69 | L3MBTL1 (1.00) | L3MBTL1ALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24944939 | 0.68 | CYP1A2 (0.59) | L3MBTL1ALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24945041 | 0.67 | L3MBTL1 (0.77) | L3MBTL1ALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24945136 | 0.67 | L3MBTL1 (0.65) | L3MBTL1ALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL24944865 | 0.66 | L3MBTL1 (0.48) | L3MBTL1ALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9431436 | 0.63 | POLB (0.56) | L3MBTL1ALOX15BCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL12225979 | 0.63 | NPC1 (0.42) | L3MBTL1NPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL5697547 | 0.62 | DAO (0.46) | L3MBTL1MRGPRX4MAPTGSK3BGSK3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040087627-A1 | Methods for the treatment of diseases using malonyl-coa decarbox ylase inhibitors | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2004-05-06 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040087627-A1 | Methods for the treatment of diseases using malonyl-coa decarbox ylase inhibitors | ME2, PC, ACACA | L3MBTL1 1071/4885ALOX15B 565/4885CYP1A2 1233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.