Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.43 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | DHPS | P49366 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846105 | 0.86 | MAPK14 (0.49) | CDC7MAPK14NUDT1CYP11B1CYP11B2 | |
| SCHEMBL6847772 | 0.85 | DYRK1A (0.47) | MAPK14NPC1RAB9ACYP11B2CYP1A2 | |
| SCHEMBL6846083 | 0.81 | CHRNB2 (0.46) | CYP11B1CYP11B2CYP1A2KDM4EALDH1A1 | |
| SCHEMBL6840695 | 0.81 | NPY5R (0.44) | NPY5RKDM4EGRIN1GRIN2B | |
| SCHEMBL6846191 | 0.81 | DHPS (0.50) | MAPK14NPC1RAB9ACYP11B1CYP11B2 | |
| SCHEMBL6846183 | 0.80 | HSD11B1 (0.45) | CDC7MAPK14NPY5RNPC1RAB9A | |
| SCHEMBL6657827 | 0.79 | CYP17A1 (0.41) | MAPK14NPC1RAB9ACYP11B1CYP11B2 | |
| SCHEMBL6840527 | 0.79 | S1PR1 (0.47) | CYP11B1CYP11B2CYP1A2ALDH1A1 | |
| SCHEMBL7021321 | 0.79 | MAPT (0.44) | MAPK14CYP11B1CYP11B2CYP1A2MAPT | |
| SCHEMBL6663847 | 0.79 | MAPK14 (0.43) | CDC7MAPK14NPC1RAB9ACYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | BAYER PHARMACEUTICALS CORPORATION | 2004-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040236110-A1 | Substituted 3-pyridyl indoles and indazoles as c17,20 lyase inhibitors | CYP17A1, IDO1, CYP21A2 | CDC7 1627/4885MAPK14 3209/4885NUDT1 2421/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.