Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL6844286

N.O=C(O)COc1ccccc1

nearest known ligand 0.95

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.95
FFAR1 O14842 1/20 0.68
KMT2A Q03164 4/20 0.66
MEN1 O00255 3/20 0.66
PTPN7 P35236 2/20 0.66
ALDH1A1 P00352 2/20 0.66
MAPT P10636 1/20 0.66
PTPN12 Q05209 1/20 0.66
LMNA P02545 1/20 0.60
SMN1; SMN2 Q16637 2/20 0.57
PPARG P37231 1/20 0.56
PPARD Q03181 1/20 0.56
ALPL P05186 1/20 0.55
ALPI P09923 1/20 0.55
ALPG P10696 1/20 0.55
POLB P06746 1/20 0.53
GLA P06280 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.53
HPGD P15428 1/20 0.53
MAPK1 P28482 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1318870 0.98 ALOX15 (1.00) ALOX15FFAR1KMT2AMEN1PTPN7
SCHEMBL8127 0.98 ALOX15 (1.00) ALOX15FFAR1KMT2AMEN1PTPN7
Methane SCHEMBL7339930 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7
SCHEMBL11312809 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7
Water SCHEMBL28773724 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7
SCHEMBL9243904 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7
SCHEMBL2168445 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7
SCHEMBL11853257 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7
Hydrochloric Acid SCHEMBL7049631 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7
SCHEMBL28510824 0.95 ALOX15 (0.95) ALOX15FFAR1KMT2AMEN1PTPN7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3710422-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES Syngenta Participations AG (CH) 2020-09-23 EP claimed
CN-111417618-A Process for preparing enantiomerically and diastereomerically enriched cyclobutaneamines and cyclobutaneamides 先正达参股股份有限公司 2020-07-14 CN claimed
CN-104130128-B The synthetic method of phenoxy acetic acid ester and intermediate thereof 浙江省诸暨合力化学对外贸易有限公司 2016-08-24 CN claimed
CN-104130128-A Synthetic method of phenoxyl acetate and intermediate thereof ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD 2014-11-05 CN claimed
EP-3710422-B1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA CROP PROTECTION AG (CH) 2026-01-07 EP disclosed
CN-111417618-B Process for preparing enantiomerically and diastereomerically enriched cyclobutane amines and amides 先正达参股股份有限公司 2023-06-30 CN disclosed
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides SYNGENTA PARTICIPATIONS AG (CH) 2021-07-06 US disclosed
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES SYNGENTA PARTICIPATIONS AG (CH) 2020-12-31 US disclosed
EP-3710422-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES Syngenta Participations AG (CH) 2020-09-23 EP disclosed
CN-111417618-A Process for preparing enantiomerically and diastereomerically enriched cyclobutaneamines and cyclobutaneamides 先正达参股股份有限公司 2020-07-14 CN disclosed
CN-104130128-B The synthetic method of phenoxy acetic acid ester and intermediate thereof 浙江省诸暨合力化学对外贸易有限公司 2016-08-24 CN disclosed
CN-104130128-A Synthetic method of phenoxyl acetate and intermediate thereof ZHEJIANG ZHUJI UNITED CHEMICALS CO LTD 2014-11-05 CN disclosed
US-20020004360-A1 Polishing slurry RENESAS ELECTRONICS CORPORATION (JP) 2002-01-10 US disclosed
CN-1222054-A Fungicide salts AGREVO UK LTD (GB) 1999-07-07 CN disclosed
EP-0682067-A1 Silica reinforced rubber composition THE GOODYEAR TIRE & RUBBER COMPANY (US) 1995-11-15 EP disclosed
EP-0611770-A2 A process for preparing acid halides ELI LILLY AND COMPANY (US) 1994-08-24 EP disclosed
US-5084568-A Process for preparing acid halides ELI LILLY AND COMPANY (US) 1992-01-28 US disclosed
US-5013854-A Process for preparing acid halides ELI LILLY AND COMPANY (US) 1991-05-07 US disclosed
EP-0381451-A1 A process for preparing acid halides ELI LILLY AND COMPANY (US) 1990-08-08 EP disclosed
US-4239675-A FOR PAINTS, PLASTICS AND CAULKING FERRIGNO THOMAS H 1980-12-16 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200407311-A1 PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY AND DIASTEREOMERICALLY ENRICHED CYCLOBUTANE AMINES AND AMIDES TBCB, ADORA2B, ADRA2B ALOX15 390/4885FFAR1 1803/4885KMT2A 1762/4885
US-11053188-B2 Process for the preparation of enantiomerically and diastereomerically enriched cyclobutane amines and amides TBCB, ADORA2B, CCNB3 ALOX15 602/4885FFAR1 1713/4885KMT2A 1609/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.