SCHEMBL6844310

SCHEMBL6844310

CCc1ccccc1C(=O)NCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KEAP1 Q14145 1/20 0.53
HPGD P15428 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
GAA P10253 2/20 0.51
LMNA P02545 1/20 0.51
HTT P42858 3/20 0.48
BCAT2 O15382 1/20 0.47
TSHR P16473 1/20 0.47
EGLN1 Q9GZT9 2/20 0.47
RAB9A P51151 1/20 0.46
ALDH1A1 P00352 1/20 0.46
F2R P25116 1/20 0.46
KMT2A Q03164 1/20 0.45
CLCN2 P51788 1/20 0.45
HDAC3 O15379 1/20 0.45
HDAC1 Q13547 1/20 0.45
MAPT P10636 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9743771 0.86 KEAP1 (0.53) KEAP1HPGDL3MBTL1GAALMNA
SCHEMBL16478564 0.85 HPGD (0.54) HPGDL3MBTL1GAALMNAHTT
SCHEMBL31448014 0.85 KEAP1 (0.62) KEAP1GAAHTTTSHREGLN1
SCHEMBL16566821 0.84 KEAP1 (0.51) KEAP1HPGDL3MBTL1GAALMNA
SCHEMBL9743474 0.84 KEAP1 (0.51) KEAP1HPGDL3MBTL1GAALMNA
SCHEMBL1276161 0.84 KEAP1 (0.51) KEAP1HPGDL3MBTL1GAALMNA
SCHEMBL7097581 0.83 L3MBTL1 (0.57) HPGDL3MBTL1GAALMNAHTT
SCHEMBL3209406 0.83 NPSR1 (0.58) HPGDL3MBTL1GAALMNAHTT
SCHEMBL17450379 0.83 HPGD (0.49) HPGDL3MBTL1GAALMNAHTT
SCHEMBL8432465 0.83 KEAP1 (0.50) KEAP1HPGDL3MBTL1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117945936-A Method for preparing 5-aminolevulinic acid hydrochloride 江苏联环药业股份有限公司 2024-04-30 CN claimed
WO-2021231410-A1 METHOD OF TREATING CANCER WITH TELOTRISAT OR A PRODRUG THEREOF TERSERA THERAPEUTICS LLC (US) 2021-11-18 WO claimed
US-20210353624-A1 METHOD OF TREATING CANCER WITH TELOTRISAT OR A PRODRUG THEREOF TERSERA THERAPEUTICS LLC 2021-11-18 US claimed
CN-113604833-A Carbon quantum dot catalyst applied to preparation of methane by carbon dioxide electroreduction and preparation method thereof 上海大学 2021-11-05 CN claimed
CN-119638584-B Preparation method of L-serine 湖南复瑞生物医药技术有限责任公司 2025-05-16 CN disclosed
CN-119638584-A Preparation method of L-serine 湖南复瑞生物医药技术有限责任公司 2025-03-18 CN disclosed
CN-117945936-A Method for preparing 5-aminolevulinic acid hydrochloride 江苏联环药业股份有限公司 2024-04-30 CN disclosed
CN-113604833-A Carbon quantum dot catalyst applied to preparation of methane by carbon dioxide electroreduction and preparation method thereof 上海大学 2021-11-05 CN disclosed
CN-106631867-A Method for synthesizing 2-benzamido-3-aryl acrylate 河南省科学院化学研究所有限公司 2017-05-10 CN disclosed
US-6758872-B2 DISPERSION OF ABRASIVE GRAINS COMPRISNG COMPOUNDS OF CERIUM, COPPER, AND/OR AMMONIUM HITACHI, LTD. (JP) 2004-07-06 US disclosed
US-6656021-B2 Process for fabricating a semiconductor device HITACHI, LTD. (JP) 2003-12-02 US disclosed
US-6656022-B2 Abrasive grains having remained after polishing are easily removed HITACHI, LTD. (JP) 2003-12-02 US disclosed
US-4584298-A CARDIOTONIC AGENTS, HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-04-22 US disclosed
EP-0052442-B1 HETEROCYCLIC COMPOUNDS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-09-11 EP disclosed
US-4503054-A VASODILATORS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-03-05 US disclosed
US-4495185-A CARDIOTONIC AND/OR HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1985-01-22 US disclosed
US-4489074-A CARDIOTONIC AGENTS, HYPOTENSIVE AGENTS IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) 1984-12-18 US disclosed
US-4423045-A CARDIOVASCULAR DISORDERS IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-12-27 US disclosed
EP-0080296-A1 Pharmaceutically active phenyl-thia-, oxa- or triazinones IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1983-06-01 EP disclosed
EP-0052442-A1 Heterocyclic compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-05-26 EP disclosed