Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ABAT | P80404 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844310 | 0.84 | KEAP1 (0.53) | KEAP1HPGDL3MBTL1LMNAGAA | |
| SCHEMBL9743771 | 0.84 | KEAP1 (0.53) | KEAP1HPGDL3MBTL1LMNAGAA | |
| SCHEMBL31448014 | 0.83 | KEAP1 (0.62) | KEAP1GAAMAPTKDM4EHIF1A | |
| SCHEMBL16566821 | 0.83 | KEAP1 (0.51) | KEAP1HPGDL3MBTL1LMNAGAA | |
| SCHEMBL9743474 | 0.83 | KEAP1 (0.51) | KEAP1HPGDL3MBTL1LMNAGAA | |
| SCHEMBL8432465 | 0.81 | KEAP1 (0.50) | KEAP1HPGDL3MBTL1LMNAGAA | |
| SCHEMBL27576446 | 0.81 | HPGD (0.47) | HPGDL3MBTL1LMNAGAABCAT2 | |
| SCHEMBL8254177 | 0.81 | L3MBTL1 (0.53) | HPGDL3MBTL1LMNAGAAKDM4E | |
| SCHEMBL9632076 | 0.79 | MAPT (0.54) | KEAP1HPGDL3MBTL1LMNAGAA | |
| SCHEMBL196585 | 0.79 | ALDH1A1 (0.55) | KEAP1HPGDLMNAGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9314431-B2 | Solubilized benzoyl small molecule | TRANSDERMAL CORP (US) | 2016-04-19 | — | — | US | claimed |
| US-9308268-B2 | Solubilized benzoyl peroxyde acne | TRANSDERMAL CORP (US) | 2016-04-12 | — | — | US | claimed |
| US-20110033402-A1 | Solubilized benzoyl small molecule | TRANSDERMAL CORP. | 2011-02-10 | — | — | US | claimed |
| US-20110027382-A1 | Solubilized benzoyl peroxyde acne | TRANSDERMAL CORP. | 2011-02-03 | — | — | US | claimed |
| US-20090304820-A1 | SOLUBILIZED BENZOYL PEROXIDE TOPICAL DRUG FORMULATION FOR THE TREATMENT OF ACNE | TRANSDERMAL CORP. | 2009-12-10 | — | — | US | claimed |
| US-9314431-B2 | Solubilized benzoyl small molecule | TRANSDERMAL CORP (US) | 2016-04-19 | — | — | US | disclosed |
| US-9308268-B2 | Solubilized benzoyl peroxyde acne | TRANSDERMAL CORP (US) | 2016-04-12 | — | — | US | disclosed |
| US-8999356-B1 | Drug delivery system | OMP, INC. (US) | 2015-04-07 | — | — | US | disclosed |
| EP-1818064-B1 | Methods of treating skin to enhance therapeutic treatment thereof | OMP INC (US) | 2013-11-13 | — | — | EP | disclosed |
| US-20120219514-A1 | COSMETIC AND PHARMACEUTICAL COMPOSITIONS COMPRISING ACE INHIBITORS AND/OR ANGIOTENSIN II RECEPTOR ANTAGONISTS | ACE APS (DK) | 2012-08-30 | — | — | US | disclosed |
| EP-2377532-A1 | Cosmetic and pharmaceutical compositions comprising ACE inhibitors and/or angiotensin II receptor antagonists for treating dermatological disorders | Ace ApS (DK) | 2011-10-19 | — | — | EP | disclosed |
| US-20110033402-A1 | Solubilized benzoyl small molecule | TRANSDERMAL CORP. | 2011-02-10 | — | — | US | disclosed |
| US-20040156793-A1 | Skin care composition and method of skin treatment | GOLDEN CHIROPRACTIC GROUP LTD. | 2004-08-12 | — | — | US | disclosed |
| US-6599513-B2 | For use in personal care and dermatological products | SEMBIOSYS GENETICS INC. (CA) | 2003-07-29 | — | — | US | disclosed |
| US-6596287-B2 | Very mild to the skin and may be easily formulated into a wide variety of personal care and dermatological products. | SEMIBIOSYS GENETICS INC. (CA) | 2003-07-22 | — | — | US | disclosed |
| US-6582710-B2 | Washed oil bodies and surfactants, emollients, fragrances, preservatives, antioxidants, emulsion stabilizing agents, moisturizers; sunscreen agents, anti-wrinkling agents, antiacne, antipsoriasis agents | SEMBIOSYS GENETICS INC. (CA) | 2003-06-24 | — | — | US | disclosed |
| US-20020114820-A1 | Products for topical applications comprising oil bodies | SEMBIOSYS GENETICS INC. (CA) | 2002-08-22 | — | — | US | disclosed |
| US-20020106337-A1 | Products for topical applications comprising oil bodies | SEMBIOSYS GENETICS INC. (CA) | 2002-08-08 | — | — | US | disclosed |
| US-20020071852-A1 | Products for topical applications comprising oil bodies | SEMBIOSYS GENETICS INC. (CA) | 2002-06-13 | — | — | US | disclosed |
| US-20020037303-A1 | Thioredoxin and thioredoxin reductase containing oil body based products | SEMBIOSYS GENETICS INC. (CA) | 2002-03-28 | — | — | US | disclosed |