Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | F2R | P25116 | 1/20 | 0.48 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HCN4 | Q9Y3Q4 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7097581 | 0.86 | L3MBTL1 (0.57) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL22515531 | 0.85 | HTT (0.56) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL6844310 | 0.85 | KEAP1 (0.53) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL14731239 | 0.85 | HPGD (0.50) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL11155899 | 0.83 | HPGD (0.49) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL17450379 | 0.82 | HPGD (0.49) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL14731238 | 0.80 | ALOX15 (0.49) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL8773450 | 0.80 | GAA (0.55) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL5954191 | 0.80 | GAA (0.57) | HPGDL3MBTL1LMNAGAAHTT | |
| SCHEMBL3135538 | 0.80 | CTSD (0.56) | HPGDL3MBTL1LMNAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9040498-B2 | 1,2,3-Triazolyl purine derivatives | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK (US) | 2015-05-26 | — | — | US | disclosed |
| US-20140011763-A1 | 1,2,3-Triazolyl Purine Derivatives | RESEARCH FOUNDATION OF THE CITY UNIVERSITY OF NEW YORK | 2014-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140011763-A1 | 1,2,3-Triazolyl Purine Derivatives | NT5C2, ENTPD5, PNP | HPGD 1974/4885L3MBTL1 1391/4885LMNA 3998/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.