Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 4/20 | 0.35 |
| ▸ | DRD2 | P14416 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6844344 | 0.99 | L3MBTL1 (0.38) | SIGMAR1L3MBTL1SLC6A2SLC6A4HTR2A | |
| SCHEMBL6839538 | 0.94 | SLC6A2 (0.40) | SIGMAR1L3MBTL1SLC6A2SLC6A4HTR2A | |
| SCHEMBL6844083 | 0.87 | MAPT (0.34) | HTR2ADRD2HTTKCNH2OPRK1 | |
| SCHEMBL6844072 | 0.85 | MAPT (0.35) | SIGMAR1HTR2ADRD2HTTDRD3 | |
| SCHEMBL6844078 | 0.85 | SIGMAR1 (0.42) | SIGMAR1L3MBTL1SLC6A2SLC6A4HTR2A | |
| SCHEMBL6844337 | 0.83 | L3MBTL1 (0.41) | SIGMAR1L3MBTL1SLC6A2SLC6A4HTR2A | |
| SCHEMBL6839506 | 0.81 | MAPT (0.35) | SLC6A2SLC6A4HTTOPRK1PRMT6 | |
| SCHEMBL6847081 | 0.71 | HTT (0.36) | SIGMAR1DRD2HTTCYP1A2CHRM2 | |
| SCHEMBL6844322 | 0.71 | HTT (0.36) | SIGMAR1DRD2HTTCYP1A2CHRM2 | |
| SCHEMBL1005114 | 0.70 | NPC1 (0.44) | SIGMAR1L3MBTL1CYP3A4MAPK1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | claimed |
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | TRPV1, TRPA1, TRPV3 | SIGMAR1 1443/4885L3MBTL1 4171/4885SLC6A2 3903/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.