Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 5/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6846908 | 0.99 | MAOA (0.49) | MAOACHRM2ACHESIGMAR1DPP7 | |
| SCHEMBL6839568 | 0.95 | MAOA (0.46) | MAOACHRM2ACHESIGMAR1DPP7 | |
| SCHEMBL6847073 | 0.88 | MAOA (0.53) | MAOACHRM2ACHESIGMAR1DPP7 | |
| SCHEMBL6844322 | 0.88 | HTT (0.36) | MAOACHRM2ACHESIGMAR1 | |
| SCHEMBL6844334 | 0.87 | MAOA (0.50) | MAOACHRM2ACHESIGMAR1DPP7 | |
| SCHEMBL6844315 | 0.87 | ADRB2 (0.35) | MAOAACHESIGMAR1 | |
| SCHEMBL6846959 | 0.83 | MAOA (0.47) | MAOACHRM2ACHESIGMAR1DPP7 | |
| SCHEMBL6839532 | 0.82 | ADRB2 (0.36) | SIGMAR1MEN1KMT2A | |
| SCHEMBL6847081 | 0.77 | HTT (0.36) | MAOACHRM2ACHESIGMAR1 | |
| SCHEMBL6844080 | 0.76 | ADRB2 (0.35) | MAOAACHESIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | claimed |
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | L'OREAL (FR) | 2004-08-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040162328-A1 | Compounds of the family of 3-alkyl-(4,5-diphenyl-imidazol-1-yl) and their use as soothing agents | TRPV1, TRPA1, TRPV3 | MAOA 753/4885CHRM2 2583/4885ACHE 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.